Ventricular septal rupture is an infrequent, but usually lethal, complication after myocardial infarction that typically occurs in elderly patients. Percutaneous closure of this complication has been performed in some cases with variable results. We report on the case of a 77-year-old female with a postinfarction ventricular septal rupture who underwent percutaneous closure using an Amplatzer device. Although the device was successfully deployed, the patient continued to have hemodynamic impairment and died within 48 hours.

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