Background: Inability to maintain balance while standing increases risk of falls in older people. The present study assessed whether center of pressure (COP) movement measured with force platform technology predicts risk for falls among older people with no manifest deficiency in standing balance.
Methods: Participants were 434 community-dwelling women, aged 63-76 years. COP was measured in six stances on a force platform. Following balance tests, participants reported their falls with 12 monthly calendars. Incidence rate ratios (IRR) with 95% confidence intervals (CI) were computed from negative binomial regression models. For the analysis, those with > or =1 fall indoors were coded "indoor fallers," those with > or =1 fall outdoors, but no indoor falls, were coded "outdoor fallers." Outcome in the models was number of falls. Analyses were repeated including only participants without fall history prior to follow-up.
Results: Among 198 fallers, there were 57 indoor and 132 outdoor fallers. The participants in the highest COP movement tertile, irrespective of the balance test, had a two- to fourfold risk for indoor falls compared to participants in the lowest COP tertile of the test. Inability to complete the tandem stance was also a significant predictor of the fall risk. The trend for increased risk for indoor falls was found also for participants in the highest COP movement tertile and without fall history. The COP movement in balance tests was not associated with outdoor falls.
Conclusion: Force platform balance tests provide valid information of postural control that can be used to predict fall risk even among older people without apparent balance problems or fall history. When the force platform is not available, tandem stance provides a screening tool to show increased fall risk in community-dwelling older people.
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http://dx.doi.org/10.1093/gerona/63.2.171 | DOI Listing |
Theranostics
January 2025
Department of Orthopedics, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Organoids, self-organized structures derived from stem cells cultured in a specific three-dimensional (3D) microenvironment, have emerged as innovative platforms that closely mimic cellular behavior, tissue architecture, and organ function. Bone organoids, a frontier in organoid research, can replicate the complex structures and functional characteristics of bone tissue. Recent advancements have led to the successful development of bone organoids, including models of callus, woven bone, cartilage, trabecular bone, and bone marrow.
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Department of Pharmacy, International Institute of Science, Arts, and Technology (IISAT), Gujranwala, Pakistan.
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December 2024
[UR 7480 VERTEX (Vertige Extrême)], University of Caen Normandy, Caen, France.
Postural control is a multisensory adaptive system performing predictive (anticipatory) and/or reactive (compensatory) actions, with varying degrees of accuracy, to maintain balance in a changing environmental context. Common instrumentation to evaluate balance includes static and dynamic force platforms; added sway-referenced perturbations on the dynamic platform constitute its main advantage. Clinical applications notwithstanding, normative data are needed for interpretation in clinical settings.
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Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
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Light Sci Appl
January 2025
Chair in Hybrid Nanosystems, Faculty of Physics, Ludwig-Maximilians-Universität München, 80539, Munich, Germany.
Multilayered van der Waals (vdW) materials are semiconductors composed of atomically thin crystal layers, held together by weak vdW forces. They offer unique crystal structures and electronic properties, distinct from conventional semiconductors, making them a promising platform for linear and nonlinear optics. In this context, the large refractive indexes given by highly polarizable transition metals, combined with excitonic resonances and unconventional crystalline structures, provides a toolbox for exploring non-linear physics and strong light-matter interactions with unprecedented opportunities for nanoscale optics.
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