AI Article Synopsis
- The study investigates transmission dynamics of Schistosoma haematobium, the causative agent of urinary schistosomiasis, focusing on the role of Bulinids in the Niger River valley.
- Malacological surveys and cercariometrical assessments revealed that the highest density of S. haematobium cercariae occurred in irrigating channels during the dry season, particularly around 3:00 PM.
- Findings suggest that targeting control efforts in these specific areas and times could enhance current mass treatment strategies for managing schistosomiasis.
Article Abstract
Background: Currently, the control of urinary schistosomiasis is mostly based on mass treatment. Characterization of Schistosoma haematobium transmission could lead to adding new methods to the control strategy.
Methods: We carried out malacological and cercariometrical surveys in irrigated perimeters of the Niger River valley. A semi-monthly follow-up was performed in three main sites of human-water contact in a village located at the border of the irrigated perimeter. Bulinids were collected during 20 min; after identification based on the shell morphology, their parasites were characterized by isoelectrofocalisation. The cercariometrical technique by differential filtration was used to evaluate the density of cercariae in every site with two 20-litre samples of water collected at various periods of the day (9, 12, 15 and 18 h).
Results: In the arm of the river, the cercariometry never showed cercariae whereas only some Bulinus truncatus, all negative, were collected. In the channels, B. truncatus and B. globosus were observed and highest density was found during the dry season. Only B. truncatus was naturally infested. Homozygote BB phenotype (characteristic of S. haematobium) was observed in all positive molluscs. Using cercariometry, more than two third of cercariae were collected at 3:00 PM.
Conclusion: Transmission of S. haematobium was primarily focused in the irrigating channels during the dry hot season at the beginning of afternoon. These results should lead to improve the output of S. haematobium control methods within irrigated areas.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.respe.2007.10.011 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness of a timed praziquantel treatment of school children in relation to seasonal transmission of urogenital schistosomiasis in Northwestern Tanzania.
Acta Trop
January 2025
Klinikum Wuerzburg Mitte GmbH, Medical Mission Hospital, Department of Tropical Medicine, Würzburg, Germany.
Background: Regular mass drug administration of praziquantel has a positive impact on reducing the burden of human schistosomiasis, however transmission still persists in many areas. To reach disease elimination; tailored interventions are needed to not only further reduce infections but also to tackle areas of persistent high prevalences of infection. One proposed approach is timed treatment based on the natural disease transmission cycle in relation to seasons.
View Article and Find Full Text PDFNuclear Intron Sequence Variation of the Complex (Mollusca: Planorbidae): Implications for Molecular Systematic Analyses.
Biology (Basel)
January 2025
Biomedical Science Research Unit, Faculty of Medicine, Mahasarakham University, Maha Sarakham 44000, Thailand.
Urinary schistosomiasis is caused by the blood fluke , which is predominantly found in Africa. The freshwater snail is its main intermediate host. The species that make up the group are genetically complex, and their taxonomic status remains controversial.
View Article and Find Full Text PDFDetection and analysis of Serpin and RP26 specific antibodies for monitoring Schistosoma haematobium transmission.
PLoS Negl Trop Dis
January 2025
Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.
Background: Schistosoma haematobium is the causative pathogen for urogenital schistosomiasis. To achieve progress towards schistosomiasis elimination, there is a critical need for developing highly sensitive and specific tools to monitor transmission in near-elimination settings. Although antibody detection is a promising approach, it is usually unable to discriminate active infections from past ones.
View Article and Find Full Text PDFBiosynthesis of Zinc Oxide Nanoparticles by Origanum majorana Aqueous Leaves Extracts, Characterization and Evaluated Against to Schistosoma haematobium.
J Biomed Mater Res B Appl Biomater
February 2025
Zoology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
Schistosomiasis, caused by Schistosoma worms, is a major neglected tropical disease in Africa, this disease is ranked as second after malaria. Nanotechnology is important for treating schistosomiasis while minimizing chemotherapy side effects. The current investigate aimed to assess the effectiveness of biosynthesized zinc oxide nanoparticles (ZnO NPs), which were used for the first time in an attempt to find alternative treatment for schistosomiasis and synthesized by Origanum majorana, and to compare them with praziquantel (PZQ), the only chemical treatment approved by the World Health Organization.
View Article and Find Full Text PDFApproaches of Inducing Tolerance to Murine Schistosomiasis mansoni applying Biomphalaria and Bulinus Proteins.
Acta Parasitol
January 2025
Parasitology Department, Theodor Bilharz Research Institute, Giza, 12411, Egypt.
Background: The freshwater snails Biomphalaria alexandrina and Bulinus trancatus are key contributors to the transmission of S. mansoni and S.haematobium, respectively, for being their intermediate hosts.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!