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http://dx.doi.org/10.1016/j.ijrobp.2007.11.024 | DOI Listing |
J Biol Eng
December 2018
1Department of Biomedical Engineering, University of Delaware, 150 Academy Street, 161 Colburn Lab, Newark, DE 19716 USA.
Metastatic recurrence is a major hurdle to overcome for successful control of cancer-associated death. Residual tumor cells in the primary site, or disseminated tumor cells in secondary sites, can lie in a dormant state for long time periods, years to decades, before being reactivated into a proliferative growth state. The microenvironmental signals and biological mechanisms that mediate the fate of disseminated cancer cells with respect to cell death, single cell dormancy, tumor mass dormancy and metastatic growth, as well as the factors that induce reactivation, are discussed in this review.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
May 2018
Minneapolis Radiation Oncology, University of Minnesota Gamma Knife Center, Waconia, Minnesota.
Syst Rev
July 2017
Department of Psychology, University of Georgia, 125 Baldwin Street, Athens, GA, 30602, USA.
Background: Delayed reward discounting (DRD), the degree to which future rewards are discounted relative to immediate rewards, is used as an index of impulsive decision-making and has been associated with a number of problematic health behaviors. Given the robust behavioral association between DRD and addictive behavior, there is an expanding literature investigating the differences in the functional and structural correlates of DRD in the brain between addicted and healthy individuals. However, there has yet to be a systematic review which characterizes differences in regional brain activation, functional connectivity, and structure and places them in the larger context of the DRD literature.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
August 2013
Int J Radiat Oncol Biol Phys
November 2012
University of Minnesota Gamma Knife, Minneapolis Radiation Oncology, Minneapolis, Minnesota, USA.
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