AI Article Synopsis
- A study was conducted on 59 elderly patients in retirement homes in Brazil, divided into two groups based on the presence or absence of denture-induced stomatitis.
- Group #1 (with stomatitis) had higher levels of Candida albicans, while other Candida species showed no significant differences.
- The activity of certain enzymes did not vary much between the groups, suggesting that enzyme secretion rates may not be crucial for the development of denture-induced stomatitis.
Article Abstract
Material And Methods: Fifty nine elders wearing complete dentures and living in retirement homes in Curitiba (southern Brazil), were divided into two groups: group #1, 26 patients with denture-induced stomatitis and group #2, 33 patients without denture-induced stomatitis. The two groups were evaluated in relation to the degree of denture-induced stomatitis, salivary fungal loads, and secretion of some histolytic enzymes.
Results: Patients from group #1 showed higher degrees of colonisation by Candida albicans (p = 0.031). Candida krusei, Candida tropicalis, and Candida parapsilosis were also isolated, but there were no differences between the groups (p > 0.05). Secretory aspartyl protease (Sap) and chondroitinase did not show significant differences among the isolated Candida spp. in the two groups. Phospholipase secretion rates were higher among the strains of C. albicans from group #2 (p = 0.036). The same behaviour was not detected for non-albicans Candida species.
Conclusions: The results could infer that differences in the secretion rates of candidal histolytic enzymes should not be imputed as imperative for the progress of denture-induced stomatitis.
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| http://dx.doi.org/10.1111/j.1741-2358.2008.00221.x | DOI Listing |
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