AI Article Synopsis
- A new method for conducting a double Friedel-Crafts reaction using N-tosyl imines and various aromatic compounds has been introduced.
- This process yields symmetric diarylmethanes and triarylmethanes with excellent regioselectivity.
- The reaction occurs efficiently at room temperature with a small amount of a catalyst made from bismuth and TMSCl.
Article Abstract
The first highly efficient double Friedel-Crafts reaction of N-tosyl imines with anisole, phenol, thioanisole and analogues has been developed to produce the corresponding symmetric diarylmethanes and triarylmethanes with high regioselectivity in the presence of a catalytic amount of Bi(2)(SO(4))(3)-TMSCl at room temperature.
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| http://dx.doi.org/10.1039/b800066b | DOI Listing |
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