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Severe hemolytic disease of the newborn from anti-e. | LitMetric

Severe hemolytic disease of the newborn from anti-e.

J Perinatol

Department of Neonatology, US Naval Hospital Okinawa and 18th Medical Group, Kadena Air Base, Kadena, Japan.

Published: March 2008

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rhesus (Rh) antibodies is a significant cause of hemolytic disease of the newborn (HDN). Here, we report a rare case of severe HDN associated with maternal antibody to Rh e. In addition to severe anemia, the infant developed thrombocytopenia, conjugated hyperbilirubinemia and cholelithiasis. Resolution of the infant's cholelithiasis occurred following treatment with ursodeoxycholic acid.

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Source
http://dx.doi.org/10.1038/sj.jp.7211897DOI Listing

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