This paper briefly reviews the researches and applications of nanotechnology in ophthalmological field recent years. Nanotechnology is the production of modern science and advanced engineering. In ophthalmological field it is generally applied on foundational investigation, medicine carrying agent, biomaterial, diagnosis and therapy. It helps us observe and control physiological and pathological phenomenon at nanometer level precisely. As new drug carriers, drug-loaded nanoparticles have lots of advantages with its targeting options and sustained drug release. As biomaterial it also has better biocompatible. It is a promising material in clinical application. The diagnosis and treatment level would be improved definitely by nanotechnology.
Download full-text PDF |
Source |
---|
Ophthalmol Sci
November 2024
Faculty of Medicine, Dentistry and Health Sciences, Department of Optometry and Vision Sciences, University of Melbourne, Parkville, Australia.
Purpose: Emerging clinical trials for inherited retinal disease (IRD) require an understanding of long-term progression. This longitudinal study investigated the genetic diagnosis and change in retinal structure and function over 10 years in rod-cone dystrophies (RCDs).
Design: Longitudinal observational follow-up study.
Ophthalmol Sci
November 2024
Department of Ophthalmology, Sichuan University West China Hospital, Chengdu, Sichuan Province, China.
Objective: To investigate the short-term blood flow changes and image features of the retina and choroid in patients who underwent carotid artery revascularization (CAR) for severe carotid artery stenosis using widefield swept-source OCT angiography (OCTA).
Design: Prospective study.
Participants: This prospective study included 112 eyes (56 eyes on the ipsilateral side and 56 eyes on the contralateral side) of 56 participants with severe carotid artery stenosis.
Purpose: To describe progression of best-corrected visual acuity (BCVA), full-field stimulus thresholds (FST), and electroretinography (ERG) over 4 years in the -related Retinal Degeneration study and to assess their suitability as clinical trial endpoints.
Design: Prospective natural history study.
Participants: Participants (n = 105) with biallelic disease-causing sequence variants in USH2A and BCVA letter scores of ≥54 were included.
J Imaging Inform Med
January 2025
Department of Ophthalmology, The Affiliated Hospital of Guilin Medical University, Guilin, China.
Optical coherence tomography angiography (OCTA) is an emerging, non-invasive technique increasingly utilized for retinal vasculature imaging. Analysis of OCTA images can effectively diagnose retinal diseases, unfortunately, complex vascular structures within OCTA images possess significant challenges for automated segmentation. A novel, fully convolutional dense connected residual network is proposed to effectively segment the vascular regions within OCTA images.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou, China.
The aim of this study is to conduct a comprehensive bibliometric analysis of CT-based adipose tissue imaging related to coronary artery disease (CAD) to investigate the dynamic development of this field. Web of Science Core Collection was used as our data source to identify relevant documents limited to articles or review articles and written in English with no time restrictions. Then we analyzed the whole trend of publications and utilized VOSviewer and Bibliometrix to conduct a bibliometric analysis including citations, keywords, countries, institutions, authors as well as co-citation analyses of cited references and sources.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!