[Clinical research on the treatment of patients with cervical carcinoma using three-dimensional conformal radiotherapy].

Objective: To explore the clinical treatment effect of three-dimensional conformal radiotherapy (3DCRT) in cervical carcinoma in comparison with traditional radiotherapy.

Methods: Totally 50 cases of cervical carcinoma were treated with 3DCRT, and another 30 cases treated with routine radiotherapy were selected during the same period as the control group. The short-term treatment effect and acute reaction in both groups were observed.

Results: The short-term effective rates of the treatment group and the control group were respectively 96% (27/28) and 97% (29/30), with no significant difference (P > 0.05). The effective rates of patients with recurrence or metastasis were respectively 92% (12/13) and 7/9. The rate of acute radiation reaction of the rectum between the treatment group and control group were respectively 46% (13/28) and 80% (24/30), with a significant difference (P < 0.05). The rate of bone marrow depression of the two groups were respectively 71% (20/28) and 63% (19/30), with no significant difference (P > 0.05), while the rate of severe bone marrow depression between two groups showed a significant difference (0 and 13%, P < 0.05). The rates of acute radiation reaction of the bladder between two groups were respectively 7% (2/28) and 3% (1/30), with no significant difference (P > 0.05).

Conclusion: The therapeutic effect of 3DCRT is similar to that of traditional radiotherapy in the treatment of cervical carcinoma, but the former treatment method has a lower rate of acute complications.