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[Using aphobazol for treatment of the emotional stress after exposure to ionizing radiation].
Patol Fiziol Eksp Ter
September 2005
Emotional stress after radiation may aggravate the course of radiation-induced diseases. The use of the selective anxiolytic aphobazol (a drug from a mercaptobenzamidasol group) corrects development of adaptive reactions to stress in the blood system and normalizes its compensatory potentialities in animals under conditions of combined influence of intensive long-term emotional stress and low-dose irradiation. In lethally irradiated animals the treatment of stressed animals with aphobazol favourably influenced the course of acute radiation disease, enhanced recovery processes in the blood system, increased the animals' survival.
View Article and Find Full Text PDFA standardized clinical and pharmacological trial of the peculiarities of action and efficacy of aphobazol, a new anxyolytic with non-benzodiazepine structure, has been conducted. An effect of the drug on different anxiety disorders has been studied. It is shown that combined anxyolytic and activating action exerted the main effect.
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