Current methods of prenatal screening for Down syndrome and other fetal abnormalities.

Clin Obstet Gynecol

Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA 22908, USA.

Published: March 2008

AI Article Synopsis

  • Prenatal diagnosis for Down syndrome is widely accessible, but criteria for who should be tested are evolving.
  • First-trimester and integrated screening have become standard options, leading to multiple accepted screening protocols for Down syndrome and other chromosome-related conditions.
  • The variety of screening choices can create confusion for both patients and healthcare providers, which highlights the need for clear information on the benefits and drawbacks of each option.

Article Abstract

Prenatal diagnosis of Down syndrome is widely available, but the determination of which patients should undergo prenatal diagnosis is changing. With the recent acceptance of first-trimester and integrated screening as a part of routine clinical practice, there are now a variety of accepted screening protocols for Down syndrome and other aneuploidies. These choices can be confusing both to both patients and providers. The following discussion is meant to outline the various options in prenatal screening, and their individual advantages and disadvantages.

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Source
http://dx.doi.org/10.1097/GRF.0b013e318160f274DOI Listing

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