AI Article Synopsis
- The study aims to investigate the increased risk of obesity and metabolic syndrome in women who had gestational diabetes and their children.
- It reviews various studies showing that mothers with a history of gestational diabetes are more likely to develop metabolic syndrome compared to those without, and this risk extends to their children, especially as they age.
- The findings highlight a concerning cycle of obesity and related health issues that may affect future generations, stressing the need for awareness and intervention.
Article Abstract
Objective: To examine the risk of obesity and metabolic syndrome in women with a history of gestational diabetes mellitus and in offspring born to mothers with gestational diabetes mellitus.
Methods: A review of studies examining the development of obesity, hypertension, metabolic abnormalities, metabolic syndrome, and type II diabetes in mothers with a history of gestational diabetes mellitus and control mothers, and offspring of mothers with a history of gestational diabetes and control mothers.
Results: Longitudinal studies demonstrate that women with a prior history of gestational diabetes mellitus and obesity are at significantly greater risk of developing metabolic syndrome than mothers with no history of gestational diabetes or obesity. The development of metabolic syndrome in children with increasing age is related to maternal gestational diabetes mellitus, maternal glycemia in the 3rd trimester, maternal obesity, neonatal macrosomia, and childhood obesity.
Conclusions: The current prevalence of obesity in both adults and children and associated disorders of blood pressure and lipid metabolism, suggest a perpetuating cycle of increasing obesity, insulin resistance, and abnormal lipid metabolism, which has ominous consequences for future generations.
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| http://dx.doi.org/10.1080/14767050801929430 | DOI Listing |
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