A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionb931s2sb4p3pa9decnc3icpvtkfmaemk): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

[Prenatal diagnosis of fetal cardiac defect]. | LitMetric

Introduction: The prevalence of congenital cardiac defects is 8 per 1000 neonates, and it's different if high or low risk populations are studied. The fetal ultrasonographic increase prenatal detection but varies from 7 to 90%.

Objectives: To know the prevalence of fetal cardiopathy and detection in high risk pregnancies.

Patients And Methods: A observational study was made in pregnancies women with 16 old week of gestation.

Results: We received a total of 3500 high-risk pregnancies and were detected 112 cases with fetal cardiopathy (3.2%). The 30% of them had a risk factor of cardiopathy. The most frequent fetal cardiac defect detected were arrhythmia in 34 fetus, septal defects in 30, valvular defects in 17, hypoplasic or absence of cardiac cavities 16, tronco-conus defects 8, and other 7 included ectopia cordis 3, cardiac tumor 2, abnormal drainage of pulmonary veins 2. The diagnosis increased every year since started study. The prenatal diagnoses suspected in fetal echocardiography were confirmed in 80% of the cases in neonatal period.

Conclusion: The detection rate of fetal cardiac defect was 3.2% in high-risk pregnancies, four times higher than general population prevalence of congenital heart disease. We found a 30% overall perinatal mortality in fetal cardiac defect. The most frequent fetal cardiac defects found in this screening were arrhythmias and septal ventricular defects in almost 50% of patients.

Download full-text PDF

Source

Publication Analysis

Top Keywords

fetal cardiac
20
cardiac defect
12
fetal
9
cardiac
8
prevalence congenital
8
cardiac defects
8
fetal cardiopathy
8
high-risk pregnancies
8
frequent fetal
8
defects
6

Similar Publications

Acute Myocardial Infarction Due to Spontaneous Coronary Artery Dissection at 36 Weeks of Pregnancy: A Case Report.

Ann Ital Chir

March 2025

Department of Medical, Surgical, Neurologic, Metabolic and Ageing Sciences, Unit of Colorectal Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Aim: Acute myocardial infarction in pregnancy (pAMI) is a rare event that is often caused by non-classical factors rather than atherosclerosis. The management of such complications requires a multidisciplinary team, and it is important to bring together the specialties involved to ensure that these teams are coordinated and ready to respond. The management of pAMI poses unique challenges because it requires consideration of both maternal and fetal well-being.

View Article and Find Full Text PDF

Objective: No clinical standard exists for intraoperative fetal cardiac monitoring during maternal-fetal surgery for fetal myelomeningocele (fMMC). This pilot study explores the feasibility of using speckle tracking echocardiography (STE)-derived functional measurements to characterize cardiac performance throughout fetoscopic fMMC and compares these measures with other common intraoperative cardiac function parameters.

Methods: Continuous fetal echocardiography was performed during fetoscopic fMMC repair with fetal heart rate assessment every 2 minutes and a 4-chamber cine clip and mitral and tricuspid Doppler inflow patterns captured every 5 minutes.

View Article and Find Full Text PDF

Maternal high-fat diet exacerbates atherosclerosis development in offspring through epigenetic memory.

Nat Cardiovasc Res

March 2025

State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Department of Physiology and Pathophysiology, Tianjin Medical University, Tianjin, China.

Maternal exposure to a Western-type diet (WD) increases the susceptibility of adult offspring to atherosclerosis, partly because fetal endothelial cells (ECs) become dysfunctional and inflamed due to risk factors transmitted via maternal-fetal blood exchange. However, the underlying mechanisms remain unclear. Here we show that maternal WD accelerates atherogenesis in adult offspring mice by regulating chromatin dynamics through activator protein-1 (AP-1) in aortic ECs, inducing inflammatory memory at the chromatin level.

View Article and Find Full Text PDF

A New Method Using the Four-Chamber View to Identify Fetuses With Subsequently Confirmed Postnatal Aortic Coarctation.

Echocardiography

March 2025

Division of Pediatric Cardiology, Department of Pediatrics, UCLA Mattel Children's Hospital, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Objective: To determine the sensitivity, specificity, and false-positive rate among fetuses suspected prenatally to have coarctation of the aorta (CoA) using size and shape measurements of the fetal heart from the four-chamber view (4CV).

Methods: This was a retrospective study of 108 fetuses identified by pediatric cardiologists to be at risk for CoA. 4CV s from the last antenatal ultrasound performed by the cardiologists were analyzed.

View Article and Find Full Text PDF

The foramen ovale is a flap in the atrial septum that is open in the fetus to allow oxygenated blood returning from the placenta to pass to the systemic circulation. In early life, the primum septal flap should close, but in 25% of people the flap does not seal fully. Most patent foramen ovale (PFO) are small and open only following Valsalva.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!