Purpose: To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX.

Material And Methods: Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry.

Results: The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001).

Conclusion: Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.

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http://dx.doi.org/10.1080/02713680701861752DOI Listing

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