In branch retinal vein occlusion (BRVO), abnormal arteriovenous crossing with vein compression, degenerative changes of the vessel wall and abnormal hematological factors constitute the primary mechanism of vessel occlusion. In general, BRVO has a good prognosis: 50-60% of eyes are reported to have a final visual acuity (VA) of 20/40 or better even without treatment. One important prognostic factor for final VA appears to be the initial VA. Grid laser photocoagulation is an established treatment for macular edema in a particular group of patients with BRVO, while promising results for this condition are shown by intravitreal application of steroids or new vascular endothelial growth factor inhibitors. Vitrectomy with or without arteriovenous sheathotomy combined with removal of the internal limiting membrane may improve vision in eyes with macular edema which are unresponsive to or ineligible for laser treatment.
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http://dx.doi.org/10.1080/02713680701851902 | DOI Listing |
Surv Ophthalmol
December 2024
Department of Ophthalmology, Taipei City Hospital, Renai Branch, Taipei, Taiwan; Department of Special Education, University of Taipei, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:
Anti-vascular endothelial growth factor (VEGF) agents administered as either monotherapy or combination with verteporfin photodynamic therapy (PDT) are the 2 dominant treatment for polypoidal choroidal vasculopathy (PCV); However, controversies remain due to small sample sizes and inconsistency in prognosis from randomized controlled trials (RCTs). In accordance with the PRISMA statement, we investigated the efficacy of PDT plus anti-VEGF combination with anti-VEGF monotherapy. This study was accepted by the International Prospective Register of Systematic Reviews (CRD42023471362).
View Article and Find Full Text PDFFront Cell Dev Biol
December 2024
Department of Ophthalmology, The Affiliated People's Hospital of Ningbo University, Ningbo, China.
Purpose: To explore the relationship between peripapillary atrophy (PPA) and diabetic retinopathy (DR), and to uncover potential mechanisms using swept-source optical coherence tomography (SS-OCT) angiography.
Methods: This cross-sectional study included 845 patients with type 2 diabetes (T2DM), who underwent detailed systemic and ophthalmic evaluations. A state-of-the-art deep learning method was employed to precisely identify the parapapillary beta and gamma zones.
Cont Lens Anterior Eye
December 2024
Centre for Eye and Vision Research (CEVR), 17W Hong Kong Science Park, Hong Kong; Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong; Research Centre for SHARP Vision (RCSV), The Hong Kong Polytechnic University, Hong Kong. Electronic address:
Purpose: This prospective study aimed to validate the translated Chinese versions of the Ocular Surface Disease Index (OSDI), 5-Item Dry Eye (DEQ-5), and Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) questionnaires and test their repeatability.
Methods: From August 2022 to July 2023, online (qualtrics.com) English and Chinese versions of OSDI, DEQ-5, and CLDEQ-8 questionnaires were distributed to residents of Hong Kong, mainland China, Taiwan, and Singapore ≥ 18 years old who could understand both written Chinese and English.
Neurol Neuroimmunol Neuroinflamm
March 2025
The Faculty of Medical & Health Sciences, Tel Aviv University.
Background And Objectives: Susac syndrome (SuS) is a rare disorder characterized by encephalopathy, branch retinal artery occlusion, and sensorineural hearing loss, often accompanied by vertigo. Recent updates to diagnostic criteria and treatment guidelines have been made. This study examines clinical manifestations; disease activity; and risk factors of disability, dependency, and return to work in patients with SuS.
View Article and Find Full Text PDFJ Neuroophthalmol
December 2024
John Sealy School of Medicine (HJY), University of Texas Medical Branch, Galveston, Texas; Department of Ophthalmology and Visual Sciences (CK), University of Texas Medical Branch, Galveston, Texas; Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program (TAN, GD), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (SAA, OAD, AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (OAD), Hashemite University, Amman, Jordan; Department of Ophthalmology (AGL), Cullen Eye Institute, Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Department of Ophthalmology (AGL), University of Texas MD Anderson Cancer Center, Houston, Texas; Texas A&M College of Medicine (AGL), Bryan, Texas; and Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa.
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