AI Article Synopsis
- Plasmacytoma is a rare localized tumor of plasma cells that can develop in the petroclival region and is associated with a high likelihood of progressing to multiple myeloma (MM) with poor outcomes.
- A case is presented involving a 65-year-old woman with a large clival plasmacytoma that led to nerve palsies; she was diagnosed with MM after a biopsy.
- The patient underwent a treatment plan that included neoadjuvant chemoradiotherapy and subsequent radical tumor resection, resulting in complete remission and no signs of local recurrence in follow-up MRIs.
Article Abstract
Background: Plasmacytoma is a localized mass of metastatic plasma cells. These lesions rarely involve the petroclival region and carry a high risk of progression to MM and poor prognosis.
Case Description: We report a 65-year-old woman who presented with a large clival plasmacytoma causing right trigeminal and abducens nerve palsies and was diagnosed with MM after transsphenoidal biopsy. She underwent neoadjuvant chemoradiotherapy followed by radical resection of the residual tumor.
Conclusion: We presented our treatment strategy including neoadjuvant chemoradiotherapy followed by radical resection of the lesion. The patient has experienced complete remission, and succeeding MRI revealed no evidence of local recurrence.
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| http://dx.doi.org/10.1016/j.surneu.2007.10.020 | DOI Listing |
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