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Background: The endoscopic full-thickness Plicator device was initially developed to provide an endoscopic treatment option for patients with GERD. Because the endoscopic full-thickness Plicator enables rapid and easy placement of transmural sutures, comparable with surgical sutures, we used the Plicator device for endoscopic treatment or prevention of GI-wall defects.
Objective: To describe the outcomes and complications of endoscopic full-thickness suturing during EMR and for the treatment of gastric-wall defects.
Design: A report of 4 cases treated with the endoscopic full-thickness suturing between June 2006 and April 2007.
Setting: A large tertiary-referral center.
Patients: Four subjects received endoscopic full-thickness suturing. The subjects were women, with a mean age of 67 years.
Interventions: Of the 4 subjects, 3 received endoscopic full-thickness suturing during or after an EMR. One subject received endoscopic full-thickness suturing for treatment of a fistula.
Main Outcome Measurements: Primary outcome measurements were clinical procedural success and procedure-related adverse events.
Results: The mean time for endoscopic full-thickness suturing was 15 minutes. In all cases, GI-wall patency was restored or ensured, and no procedure-related complications occurred. All subjects responded well to endoscopic full-thickness suturing.
Limitations: The resection of one GI stromal tumor was incomplete. Because of the Plicator's 60F distal-end diameter, endoscopic full-thickness suturing could only be performed with the patient under midazolam and propofol sedation. The durable Plicator suture might compromise the endoscopic follow-up after EMR.
Conclusions: The endoscopic full-thickness Plicator permits rapid and easy placement of transmural sutures and seems to be a safe and effective alternative to surgical intervention to restore GI-wall defects or to ensure GI-wall patency during EMR procedures.
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| http://dx.doi.org/10.1016/j.gie.2007.10.051 | DOI Listing |
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