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Neutrophilic Dermatosis of the Hands: A Case Report.
Acta Dermatovenerol Croat
December 2023
Nooshin Bagherani, MD, PhD, Tehran University of Medical Sciences, Italy Street, Tehran, Iran;
Article Synopsis
- - Neutrophilic dermatosis of the hands (NDDH) is a recently identified localized variant of Sweet's syndrome, characterized by violaceous papulonodules on the hands, lacking true vasculitis findings, as outlined by Strutton et al. (1996) and Galaria et al. (2000).
- - A 46-year-old man presented with a painful, ulcerative lesion on his left hand, which started as a small papule and progressively worsened despite various treatments for suspected bacterial or fungal infections.
- - Upon examination, the lesion measured 4×7 cm and was associated with atrophic scars from previous similar lesions; laboratory tests indicated leukocytosis and altered liver function
A Case of Bullous Sweet's Syndrome Associated With Esophageal Adenocarcinoma.
Cureus
January 2024
Dermatology, University of South Florida Morsani College of Medicine, Tampa, USA.
Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis, characteristically presents with fever, dermal neutrophilic infiltrates, and neutrophilia. It typically manifests as tender erythematous plaques; however, various variants are documented, including bullous. Malignancy-associated Sweet's syndrome (MASS) can present as a paraneoplastic syndrome in those with established cancers or with undiagnosed malignancies.
View Article and Find Full Text PDFResponse of autoimmune and inflammatory disorders in myelodysplastic syndromes to 5-azacytidine: report of two cases and literature review.
Ann Palliat Med
August 2021
Department of Hematology, the First Affiliated Hospital of China Medical University, Shenyang, China.
Paraneoplastic autoimmune and inflammatory disorders are often associated with myelodysplastic syndromes (MDS). The etiopathogenesis of MDS-associated autoimmune and inflammatory disorders is still unclear and treatment options are limited. Patients with MDS are at high risk of infections, which can be increased by the use of steroids.
View Article and Find Full Text PDFTransformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing sweet syndrome.
Dermatol Reports
March 2021
Research Division, Hospital de Especialidades Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
The Sweet's syndrome, is an inflammatory skin disorder characterized by extensive infiltration of neutrophils in the dermis with extension to the subcutis, known as acute febrile neutrophilic dermatosis. It may occur as a paraneoplastic syndrome. To our knowledge, there are currently few reports about transformation of a myelodysplastic syndrome to acute myeloid leukemia and concurrent necrotizing Sweet syndrome in the literature.
View Article and Find Full Text PDFNeuro-Sweet syndrome - a rare differential diagnosis in aseptic meningoencephalitis.
Neurol Res Pract
November 2019
Department of Epileptology, University Hospital for Neurology, Eberhard Karls University, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.
Acute febrile neutrophilic dermatosis (Sweet's syndrome) is a dermatological entity, which may be associated with malignancies, drugs, and infections and which is characterized by high fever, elevated neutrophils, and tender erythematous skin lesions. Involvement of the nervous system - Neuro-Sweet syndrome (NSS) - is rare, manifesting most commonly with an encephalitic syndrome in addition to fever and dermal lesions. Here, we report an unusual case of NSS in a Caucasian male patient in the setting of B-cell-lymphocytosis, with encephalitis preceding dermal lesions.
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