We have discovered functionalized multiwalled carbon nanotubes with reduced protein-binding, cytotoxicity, and immune response and the associated structure-activity relationships using in silico surface molecular diversity design, combinatorial library synthesis, and multiple biological screenings. Our results demonstrated the general utility of the nanocombinatorial library approach in nanomedicine and nanotoxicity research.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/nl0730155 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Laser ablation propulsion is an important micro-propulsion system for microsatellites. Polymers with carbon added and carbon-based nanomaterial have been demonstrated as propellants with high impulse coupling coefficient (C). Among them, the carbon nanotube film exhibits a low ablation threshold fluence of 25 mJ/cm, which shows its potential for propulsion under low laser fluence.
View Article and Find Full Text PDFMetagenomic insights into efficiency and mechanism of antibiotic resistome reduction by electronic mediators-enhanced microbial electrochemical system.
J Hazard Mater
January 2025
Engineering Research Center of Groundwater Pollution Control and Remediation (Ministry of Education), College of Water Sciences, Beijing Normal University, No 19, Xinjiekouwai Street, Beijing 100875, China. Electronic address:
Electronic mediators are an effective means of enhancing the efficiency of microbial electrochemical electron transfer; however, there are still gaps in understanding the strengthening mechanisms and the efficiency of removing antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria (ARB). This study systematically elucidates the effects of various electron mediators on bioelectrochemical processes, electron transfer efficiency, and the underlying mechanisms that inhibit ARG propagation within sediment microbial fuel cell systems (SMFCs). The results indicate that the addition of electron mediators significantly increased the output voltage (33.
View Article and Find Full Text PDFAntimicrobial and Antibiofilm Activities of Urinary Catheter Incorporated with ZnO-Carbon Nanotube.
ACS Appl Bio Mater
January 2025
College of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae 50832, Republic of Korea.
Urinary tract infections are among the most common nosocomial infections, with the majority being catheter-associated urinary tract infections (CAUTIs). This study demonstrated that an antimicrobial and antibiofilm urinary catheter containing zinc oxide-carbon nanotubes (ZnO-CNT) can inhibit CAUTIs in patients. ZnO-CNT polymers were synthesized by mixing ZnO and CNT using a high-shear mixer, and the synthesized ZnO-CNT polymers were incorporated into a silicone matrix to produce a ZnO-CNT urinary catheter.
View Article and Find Full Text PDFTargeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically 'cold' tumor models.
Front Immunol
January 2025
Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Introduction: Hyperthermia is an established adjunct in multimodal cancer treatments, with mechanisms including cell death, immune modulation, and vascular changes. Traditional hyperthermia applications are resource-intensive and often associated with patient morbidity, limiting their clinical accessibility. Gold nanorods (GNRs) offer a precise, minimally invasive alternative by leveraging near-infrared (NIR) light to deliver targeted hyperthermia therapy (THT).
View Article and Find Full Text PDFA solar-powered electrocoagulation process with a novel CNT/silver nanowire coated basalt fabric cathode for effective oil/water separation: From fundamentals to application.
J Environ Manage
January 2025
Xinjiang Key Laboratory of Separation Material and Technology, The Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:
Electrocoagulation (EC) has proven its high efficiency and environmental sustainability for treating several types of wastewaters. However, the primary drawbacks of the conventional EC process are the suitable electrode materials and the relatively high cost due to the requirement for electric energy. To overcome these practical challenges, this study investigated effective oil/water separation by a solar-powered electrocoagulation (SPEC) process using a novel highly conductive basalt fabric (BF) cathode.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!