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Financial assistance for snakebite envenoming by OECD nations.
Trans R Soc Trop Med Hyg
January 2025
Northern Sydney Local Health District, Hornsby Hospital, Palmerston Road, Sydney, NSW 2077, Australia.
Background: The World Health Organization re-established snakebite as a neglected tropical disease in 2017. An overview is provided on snakebite financial assistance in relation to the policy landscape change.
Methods: The Organisation for Economic Co-operation and Development Creditor Reporting System database was searched and 184 results obtained from 1999 to 2022 underwent simple Excel analysis.
Developmental dynamics mimicking inversely engineered pericellular matrix for articular cartilage regeneration.
Biomaterials
December 2024
School of Medicine, Nankai University, Tianjin, 300071, PR China; Institute of Orthopedics, The First Medical Center, Chinese PLA General Hospital, Beijing Key Lab of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, No. 28 Fuxing Road, Haidian District, Beijing, 100853, PR China; National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation, Beijing, 100853, PR China. Electronic address:
The mechanical mismatch of scaffold matrix-mesenchymal stem cells (MSCs) has been a longstanding issue in the clinical application of MSC-based therapy for articular cartilage (AC) regeneration. Existing tissue-engineered scaffolds underestimate the importance of the natural chondrocyte pericellular matrix (PCM). Here, we reveal the temporal and spatial characteristics of collagen distribution around the chondrocytes.
View Article and Find Full Text PDFMinimally invasive reduction of irreducible, sagittally unstable peritrochanteric fractures: Novel technique and early results.
Chin J Traumatol
December 2024
Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. Electronic address:
Purpose: The management of irreducible, sagittally unstable peritrochanteric fractures presents a significant challenge due to the inability to achieve closed reduction using conventional techniques. This study introduces a novel minimally invasive technique leveraging the mechanical advantage principle with long, angled hemostatic clamps.
Methods: A retrospective review was performed on 16 patients who sustained sagittally unstable peritrochanteric fractures and underwent a percutaneous hemostatic clamp leverage reduction procedure.
Recent Advances in Regenerative Endodontics: A Review of Current Techniques and Future Directions.
Cureus
November 2024
Endodontics, Private Clinic, Khobar, SAU.
Regenerative endodontics is a rapidly evolving discipline focused on biologically restoring the pulp-dentin complex to revive vitality in non-vital teeth. Unlike traditional endodontic therapies that rely on inert materials to preserve structure, regenerative techniques aim to re-establish natural structure and function by harnessing advancements in tissue engineering. This narrative review examines recent progress in stem cell applications, scaffold development, signaling molecules, and clinical protocols that contribute to successful regenerative outcomes.
View Article and Find Full Text PDFThe RNA-binding protein CMSS1 promotes the progression of non-small cell lung cancer by regulating the telomerase protein subunit hTERT.
Life Sci
December 2024
Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China. Electronic address:
Aims: High telomerase activity has been detected in over 85 % of tumors, with the activation of hTERT being the most crucial mechanism for re-establishing telomerase activity. Activation of hTERT maintains telomere length in cells, enabling cancer cells to proliferate indefinitely. Nevertheless, the specific mechanism of telomerase activation in non-small cell lung cancer (NSCLC) remains unclear, and post-transcriptional regulation of hTERT could be a potential activation mechanism.
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