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Rotational Atherectomy to Treat in-Stent Recurrent Protruding Calcified Nodule.
JACC Case Rep
January 2025
Cardiovascular Division, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
A 73-year-old man presented with acute coronary syndrome secondary to stent failure. Intravascular imaging identified a recurrent protruding calcific nodule as the mechanism, which was effectively treated with low-speed rotablation, resulting in ablation of the nodule allowing the application of a drug-coated balloon.
View Article and Find Full Text PDFMetabolism-Related Adipokines and Metabolic Diseases: Their Role in Osteoarthritis.
J Inflamm Res
January 2025
Department of Rehabilitation Medicine, Binzhou Medical University Hospital, Binzhou, Shandong, People's Republic of China.
Osteoarthritis (OA) affects several joints but tends to be more prevalent in those that are weight-bearing, such as the knees, which are the most heavily loaded joints in the body. The incidence and disability rates of OA have continued to increase and seriously jeopardise the quality of life of middle-aged and older adults. However, OA is more than just a wear and tear disease; its aetiology is complex, and its pathogenesis is poorly understood.
View Article and Find Full Text PDFPrevalence of the Cardiovascular-Kidney-Metabolic Syndrome in 3 Chinese Cohorts.
JACC Asia
January 2025
Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Association of serum magnesium and calcium with metabolic syndrome: a cross-sectional study from the Qatar-biobank.
Nutr Metab (Lond)
January 2025
Department of Population Medicine, College of Medicine, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar.
Background And Objectives: Metabolic syndrome (MetS) and its constituent comorbidities, along with mineral imbalances, pose a significant health burden in the Qatari population. Although Magnesium (Mg) and Calcium (Ca) have been individually linked to MetS, the impact of the calcium-to-magnesium ratio (Ca: Mg) on MetS remains unclear, especially in the adult population of Qatar. In this study, we aim to investigate the association between the total serum concentrations of Ca, Mg and Ca: Mg ratio with the outcome of MetS.
View Article and Find Full Text PDFClinical integration of germline findings from a tumor testing precision medicine program.
BMC Cancer
January 2025
Department of Medicine, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada.
Background: Integrating germline genetic testing (GGT) recommendations from tumor testing into hereditary cancer clinics and precision oncology trials presents challenges that require multidisciplinary expertise and infrastructure. While there have been advancements in standardizing molecular tumor boards, the implementation of tumor profiling for germline-focused assessments has only recently gained momentum. However, this progress remains inconsistent across institutions, largely owing to a lack of systematic approaches for managing these findings.
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