We compared measured resting energy expenditure (MREE) and predicted resting energy expenditure (PREE) in 398 chronically ill children and found a wide variability for %MREE/PREE (standard deviation +/- 27.2). Bland-Altman analysis also suggested poor agreement between MREE and PREE (mean bias, 43.2 kcal; range, -645 to 1118.1 kcal). Our findings suggest that resting energy expenditure should be measured in chronically ill children.

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