Background: To characterize adenoviral (ADV) infection, the clinical symptoms, laboratory findings and serum cytokine concentrations were evaluated in ADV patients and compared with those in patients with respiratory syncytial virus (RSV) infections.
Methods: A total of 63 patients who had been diagnosed with ADV infections or RSV on an antigen detection test were enrolled in the present study between December 2002 and March 2004. Forty patients had RSV infection and 23 patients had ADV infection. Serum cytokine (interleukin [IL]-4,6 and interferon [IFN]-gamma) concentrations were analyzed. Concentration of IL-6 in both infection groups was analyzed regardless of whether the patients had been given steroids (dexamethaxone or prednisolone). In addition, IL-6 levels were measured on day 1 and 4 of hospitalization.
Results: A strong inflammatory response was observed in patients with ADV infection. Serum IL-6 levels in patients with ADV infection on day 4 of hospitalization were significantly higher than those in patients without steroids treatment or in patients with RSV infection. IL-4, and IFN-gamma were not significantly different.
Conclusion: Patients with ADV infections who were given steroids had a temporary increase of IL-6, which might have indicated the development of a severe clinical course if not been administered.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1442-200X.2007.02522.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Imbalanced VWF-ADAMTS13 axis contributes to the detrimental impact of a preceding respiratory tract infection on stroke.
Blood Adv
January 2025
University of Iowa, Iowa city, Iowa, United States.
Respiratory tract infections (RTIs) caused by bacteria or viruses are associated with stroke severity. Recent studies have revealed an imbalance in the von Willebrand factor (VWF)-ADAMTS13 axis in patients with RTIs, including COVID-19. We examined whether this imbalance contributes to RTI-mediated stroke severity.
View Article and Find Full Text PDFTargeted Enrichment Sequencing Utilizing a Respiratory Pathogen Panel for Genomic Wastewater-Based Viral Epidemiology in Uruguay.
Food Environ Virol
January 2025
Laboratorio de Ecología Viral y Virus Zoonóticos, Unidad Académica de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Av. Alfredo Navarro 3051, 11600, Montevideo, Uruguay.
Human respiratory and enteric viruses are responsible for substantial morbidity and mortality worldwide. Wastewater-based epidemiology utilizing next-generation sequencing serves as an effective tool for monitoring viral circulation dynamics at the community level. However, these complex environmental samples are often laden with other microorganisms and host genomic material, which can hinder the sensitivity of viral detection.
View Article and Find Full Text PDFDistribution and antifungal susceptibility of species causing vulvovaginal candidiasis and urinary tract infection in Medlatec healthcare system, Ha Noi city, Vietnam in 2023.
Ther Adv Infect Dis
January 2025
Department of Medical Parasitology, Military Medical University, No. 160 Phunghung Road, Hadong District, Hanoi 100000, Vietnam.
Background: Vulvovaginal candidiasis and urinary tract infections caused by are common diseases. While the most common causative agent is , other species, such as non-, can also be responsible. Susceptibility to antifungal drugs varies among species, but there is very limited information available from Vietnam.
View Article and Find Full Text PDFNavigating the landscape of neoadjuvant immunotherapy for NSCLC: progress and controversies.
Ther Adv Med Oncol
January 2025
Department of Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, No. 9 Beiguan Street, Tongzhou District, Beijing 101149, China.
Recently, attention has increasingly centered on non-small-cell lung cancer (NSCLC) with immune checkpoint inhibitors application. Numerous clinical studies have underscored the potential of immunotherapy in treating resectable NSCLC, highlighting its role in improving patient outcomes. However, despite these promising results, there is ongoing debate regarding the efficacy of immunological combination therapy strategies, the prevalence of treatment-related side effects, the identification of predictive biomarkers, and various other challenges within the neoadjuvant context.
View Article and Find Full Text PDFA novel multilayer antimicrobial urinary catheter material with antimicrobial properties.
Mater Adv
December 2024
Cardiff University School of Pharmacy and Pharmaceutical Sciences, Redwood Building King Edward VII Ave Cardiff CF10 3NB UK
Urinary catheters are commonly used in medical practice to drain and monitor urine of patients. However, urinary catheterisation is associated with the risk of developing catheter-associated urinary tract infections (CAUTIs), which can result in life-threatening sepsis that requires antibiotics for treatment. Using the layer-by-layer (LbL) technique, we assembled a multilayer catheter comprising nine quadruple layers (9QL) of alginate, chlorhexidine (CHX), alginate and poly(β-amino ester) (PBAE) built upon an amino-functionalised silicone.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!