AI Article Synopsis
- Leishmaniasis affects around 12 million people globally, with approximately 400,000 new cases annually, particularly in Brazil and Latin America.
- The study focuses on improving understanding of mucosal leishmaniasis through insights from the Immunology and Otolaryngology Departments at a university hospital in Bahia.
- Cutaneous leishmaniasis is most prevalent in the New World, while mucosal lesions, primarily caused by L. braziliensis, can develop along with or long after cutaneous symptoms, affecting areas like the nose, lips, and throat, with both the parasite and host immune response playing roles in the disease's impact.
Article Abstract
Unlabelled: Leishmaniasis has been documented in several countries, with an estimated prevalence of 12 million people and an incidence at around 400,000 new cases per year. Leishmaniasis in the New World is one the major endemic diseases in Brazil and Latin America.
Objective: The aim of this study was to add to the current knowledge on mucosal leishmaniasis, bringing the experience of the Immunology and Otolaryngology Departments in the Professor Edgar Santos University Hospital of the Federal University of Bahia.
Conclusion: Cutaneous leishmaniasis is the most common form of New World Leishmaniasis; mucosal legions may occur simultaneously or after years of disease. Mucosal leishmaniasis is caused mainly by L. braziliensis braziliensis; although the nasal mucosa is the most affected area, lesions may be found on the lips, mouth, pharynx and larynx. In addition to parasite-related factors, the host immune response may be involved in the pathogenicity of lesions in mucosal leishmaniasis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450602 | PMC |
| http://dx.doi.org/10.1016/S1808-8694(15)31181-2 | DOI Listing |
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