Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1126/science.319.5865.900c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Golgi apparatus is a critical organelle responsible for intracellular trafficking and signaling, orchestrating essential processes such as protein and lipid sorting . Dysregulation of its function has been implicated in various pathologies, including obesity, diabetes, and cancer, highlighting its importance as a potential therapeutic target. Despite this, the development of tools to selectively target the Golgi in specific cell types remain a significant unmet challenge in imaging and drug discovery.
View Article and Find Full Text PDFAdaptation to Climate Change in Viticulture: The Role of Varietal Selection-A Review.
Plants (Basel)
January 2025
Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Viticulture faces unprecedented challenges due to the rapidly changing climate, particularly in regions like the Mediterranean Basin. Consequently, climate change adaptation strategies are crucial in viticulture, with short-term strategies being widely used despite increasing concerns about their sustainability, and long-term strategies considered promising, though costly. A promising but understudied strategy is varietal selection, as grapevines exhibit vast intervarietal diversity with untapped potential for climate-resilient varieties.
View Article and Find Full Text PDFSolvent-Driven Self-Assembly of Discrete Ni(II)-Azide Complexes: Unraveling Unusual Behavior in Mimicking Jack Bean Urease.
Inorg Chem
January 2025
Department of Chemistry, University College of Science, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.
The well-known inhibitory strength of 3d metal Schiff base complexes against urease enzymes has long been acknowledged, but their untapped potential to act as ureolytic mimics of active metallobiosites remained unexplored. To break the new ground, we present pyrrolidine-based mononuclear Ni(II)-azide complex {[NiL(HL)(N)]·1.5(HO)} using the N,N,O donor ligand, namely ()-4-bromo-2-(((2-(pyrrolidin-1-yl)ethyl)imino)methyl)phenol.
View Article and Find Full Text PDFInnovative method integrates play fairway analysis supported with GIS and seismic modeling for geothermal potential evaluation in a basement reservoir.
Sci Rep
January 2025
Faculty of Earth and Environmental Sciences and Engineering, Institute of Exploration Geosciences, University of Miskolc, Miskolc, Hungary.
The growing demand for clean and sustainable energy sources has prompted the investigation of numerous renewable and ecologically friendly options. Among these, geothermal energy is particularly noteworthy because of its widespread availability, compact size, and consistent, weather-independent power production. A geothermal play fairway analysis (GPFA) model was created for the study area, which is located in Békés county, southeastern Hungary.
View Article and Find Full Text PDFRealizing the Untapped Potential of Stress Perfusion CMR in Medicare's Aging Population.
JACC Cardiovasc Imaging
January 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, Guy's and St Thomas' Hospital, London, United Kingdom; Cardio-Oncology Centre of Excellence, Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!