Objective: Recommendations and/or guidelines represent a popular way of integrating evidence-based medicine into clinical practice. The 3E Initiatives is a multi-national effort to develop recommendations for the management of rheumatic diseases, which involves a large number of experts combined with practising rheumatologists addressing specific questions relevant to clinical practice.
Methods: Ten countries participated in three rounds of discussions and votes concerning the management of AS. A set of nine questions was formulated in the domains of diagnosis, monitoring and treatment, after a Delphi procedure. A literature search in MedLine was conducted. Predefined outcome parameters for the domains of diagnosis, monitoring and treatment were assessed. The evidence to support each proposition was evaluated and scored. After discussion and votes, the final recommendations were presented using brief statements by each national group, following which the final international recommendations were formulated.
Results: A total of 2699 papers were found and 467 were selected for analysis. Twelve key recommendations were developed: three in the domain of diagnosis addressing general diagnostic considerations, early AS diagnosis and general practitioners' referral recommendations; three concerning monitoring of AS disease activity, severity and prognosis; six concerning pharmacological treatment (except biologics): non-steroidal anti-inflammatory drugs/COX-II inhibitors, bisphosphonates and treatment of enthesitis. The compiled agreement among experts ranged from 72% to 93%.
Conclusion: Recommendations for the management of AS were developed using an evidence-based approach followed by expert/physician consensus with high level of agreement. Involvement of a larger and more representative group of rheumatologists may improve their dissemination and implementation in daily clinical practice.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/rheumatology/kem348 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Successful staged surgery for advanced esophageal cancer after conversion pancreatoduodenectomy with pancreaticogastrostomy.
Clin J Gastroenterol
January 2025
Department of Gastroenterological Surgery and Pediatric Surgery, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu City, Gifu Prefecture, 501-1194, Japan.
Background: Complex surgery during initial cancer treatment can limit surgical options when planning management of a secondary malignancy. Subtotal esophagectomy and pancreatoduodenectomy are the most invasive and difficult procedures in gastroenterological surgery. Surgical cases in which subtotal esophagectomy was performed after pancreatoduodenectomy with pancreaticogastrostomy are extremely rare and challenging procedures due to the resulting complicated anatomical changes.
View Article and Find Full Text PDFAssessing the impacts of forest cover change on carbon stock and soil moisture dynamics using geospatial techniques: a case study of Nensebo forest, Southern Ethiopia.
Environ Monit Assess
January 2025
Department of Natural Resource Management, College of Agriculture and Veterinary Medicine, Jimma University, Jimma, Ethiopia.
Assessing the impacts of forest cover change on carbon stock and soil moisture dynamics is critical for understanding environmental degradation and guiding sustainable land management. This study evaluates the effects of forest cover change on carbon stock and soil moisture dynamics in Nensebo Forest from 1993 to 2023 using geospatial techniques. Landsat imagery including TM (1993), ETM + (2009), and OLI/TIRS (2023) were used.
View Article and Find Full Text PDF[Secondary stroke prevention].
Radiologie (Heidelb)
January 2025
Klinik für Diagnostische und Interventionelle Neuroradiologie, Kirrberger Straße, Gebäude 90, 66421, Homburg/Saar, Deutschland.
Background: The treatment of strokes is based on two pillars: the efficient management of acute strokes to minimize permanent neurological deficits, and secondary prevention to avoid recurrence.
Objective: To summarize current recommendations for secondary stroke prevention.
Materials And Methods: Guidelines and recent studies on the most common causes of strokes, and their treatment and prevention are reviewed.
Clinical Issues of Chinese Medicine Usage in Integrated Medicine Treatment for Colorectal Cancer: Recommendations of Chinese Guideline.
Chin J Integr Med
January 2025
Department of Oncology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Bijing, 100091, China.
Purpose: This report details the recommendations of a Nursing Best Practice Working Group, which aims to advance best practice in the use of 5-aminolevulinic acid (5-ALA) fluorescence-guided surgery (FGS) in patients with high-grade glioma (HGG).
Design: Quality Improvement Project.
Methods: These recommendations were gathered during a meeting of a Nursing Best Practice Working Group comprising expert nurses and practice administrators from five US centers of excellence in the management of HGG.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!