Variation of a newcastle disease virus hemagglutinin-neuraminidase linear epitope.

J Clin Microbiol

Zoonotic Disease Institute, Seoul National University, San 56-1, Shillim-Dong, Gwanak-Gu, Seoul 151-742, South Korea.

Published: April 2008

Fifty-six Newcastle disease virus strains collected from 2000 to 2006 could be grouped into subgenotype VIId. However, they displayed cumulative mutations in and around the linear epitope of hemagglutinin-neuraminidase (residues 345 to 353) with time. The antigenicities of the variants that became predominant in Korea differ from each other and from the wild type.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292945PMC
http://dx.doi.org/10.1128/JCM.00187-08DOI Listing

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