Review of David Rieff's Swimming in a sea of death: a son's memoir. Rieff is the son of writer Susan Sontag.
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Laparoscopic Pudendal Nerve Release at the Level of Sacrospinous Ligament.
Int Urogynecol J
January 2025
Vitale Private Obstetrics & Gynecology Hospital, Antalya, Türkiye.
Introduction And Hypothesis: Pudendal nerve release can be managed by the laparoscopic approach for pudendal nerve entrapment.
Methods: This is a case report of a stepwise demonstration of the technique with narrated video footage. A 71-year-old woman, gravid 7, parity 3, abortion 4, live births 3 vaginal delivery, complained of pain while sitting.
Protective Efficacy of Decreasing Antigen Doses of a Subcellular Vaccine Against Ovine Enzootic Abortion in a Pregnant Sheep Challenge Model.
Vaccines (Basel)
January 2025
Moredun Research Institute, Pentlands Science Park, Penicuik, Midlothian EH26 0PZ, UK.
Background/objective: , the cause of ovine enzootic abortion, is a zoonotic bacterial pathogen and one of the most infectious causes of foetal death in sheep worldwide. Although the disease can be controlled using commercial inactivated and live whole-organism vaccines, there are issues with both, particularly concerning efficacy and safety. Recently, we have described the development of a new COMC (chlamydial outer membrane complex) vaccine based on a detergent-extracted outer membrane protein preparation of the pathogen, which can be delivered in a single inoculation and is both efficacious and safe.
View Article and Find Full Text PDFLive Plague Vaccine Development: Past, Present, and Future.
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January 2025
Laboratory for Plague Microbiology, Especially Dangerous Infections Department, State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Russia.
During the last 100 years, vaccine development has evolved from an empirical approach to one of the more rational vaccine designs where the careful selection of antigens and adjuvants is key to the desired efficacy for challenging pathogens and/or challenging populations. To improve immunogenicity while maintaining a favorable reactogenicity and safety profile, modern vaccine design must consider factors beyond the choice of target antigen alone. With new vaccine technologies currently emerging, it will be possible to custom-design vaccines for optimal efficacy in groups of people with different responses to vaccination.
View Article and Find Full Text PDFThe Mental Health of Older People Living in Nursing Homes in Northern Portugal: A Cross-Sectional Study Protocol.
Nurs Rep
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School of Nursing, University of Minho, 4710-057 Braga, Portugal.
: In Portugal, evidence regarding the mental health of institutionalized older people is limited, leaving this area poorly described and the mental health needs of this population largely unknown. This research aims to describe the mental health of older persons residing in nursing homes in Northern Portugal. : A cross-sectional study will be conducted.
View Article and Find Full Text PDFProtocol of an Efficacy Study on Nursing Consultation in Weight Management and Metabolic Syndrome Based on the Carbohydrate-Insulin Theory in Individuals with First-Episode Psychosis.
Nurs Rep
December 2024
Psychiatry Department, Basurto University Hospital, 48013 Bilbao, Spain.
: Individuals with severe mental illness live, on average, up to 30 years less than the general population, with cardiovascular disease being the leading cause of death. Metabolic syndrome (MetS) plays a significant role in this, making it crucial to manage this issue in individuals with psychosis at the onset of the illness. The approach to managing this issue has evolved from a focus on calorie counting to a deeper understanding of hormone function, particularly the role of insulin resistance in MetS.
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