We analyzed factors associated with skin erosion in 55 patients treated with deep brain stimulation (Kinetra or Soletra) for Parkinson's (PD) or other diseases. Nine of 55 patients developed erosion, all of whom were PD patients who had been fitted with a Kinetra device (r = 0.9292; p < 0.005). Erosions may be due to an increased pressure over the skin resulting from the larger size and weight of the Kinetra device. Alternatively, erosions in patients with the Kinetra device and bilateral leads may arise from the larger size of the 2 extension wires into the same subcutaneous tunnel and from the larger size of the 2 close parieto-occipital connections on the same cranial side. In PD patients, erosions were not related to age, immobility or PD severity. Specific studies examining the role of the skin of PD patients in erosion development and the use of smaller stimulation systems may help minimize the erosion rate.
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http://dx.doi.org/10.1159/000116216 | DOI Listing |
Stereotact Funct Neurosurg
May 2021
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Introduction: A wide range of pulse widths (PWs) has been used in globus pallidus internus (GPi) deep brain stimulation (DBS) for dystonia. However, no specific PW has demonstrated clinical superiority, and the paradigm may differ among DBS centers.
Objective: To investigate how different paradigms of PWs in GPi DBS for dystonia affect implantable pulse generator (IPG) longevities and energy consumption.
Acta Neurochir (Wien)
October 2019
Service de Neurochirurgie, Centre Hospitalier Universitaire de Clermont Ferrand, Clermont Ferrand, France.
Background: Battery life of the most commonly used implantable pulse generators in deep brain stimulation is limited. Device replacement is costly and may expose patients to additional risks. Driven by the observation that in our experience newer generation devices seemed to need earlier replacement than the older generation, we aimed to retrospectively analyze the battery life of two generations of non-rechargeable devices, manufactured by a single company (Medtronic, USA).
View Article and Find Full Text PDFNeuromodulation
June 2020
Department of Neurosurgery, Charité University Medicine Berlin, Berlin, Germany.
Background: Deep brain stimulation (DBS) is an approved therapy option for movement disorders such as Parkinson's disease (PD), essential Tremor (ET), and dystonia. While current research focuses on rechargeable implantable pulse generators (IPGs), little is known about changes of the motor functions after IPG replacement and the consequences of additionally implanted hardware.
Objective: To assess changes of the motor functions, the therapy impedances, and the total electric energy delivered (TEED) after elective IPG replacement.
World Neurosurg
July 2019
Department of Neurosurgery, University Medical Center Schleswig-Holstein, Campus Kiel, Christian-Albrechts University Kiel, Kiel, Germany.
Objective: Generators implanted for deep brain stimulation must be replaced after several years. If a Kinetra generator is replaced by the Activa-PC, an adaptor will be required to attach it to the original extension cables. On the basis of our clinical impression that the battery life of the Active-PC generator was shorter when an adaptor was used, we performed this retrospective study.
View Article and Find Full Text PDFBrain Stimul
December 2019
Movement Disorders Institute and Department of Neurology, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.
Background: People with Parkinson's disease (PD) treated with deep brain stimulation (DBS) with non-rechargeable implantable pulse generators (IPGs) require elective IPG replacement operations involving surgical and anesthesiologic risk. Life expectancy and the number of replacements per patient with DBS are increasing.
Objective: To determine whether IPG longevity is influenced by stimulation parameters alone or whether there is an independent effect of the number of battery replacements and IPG model.
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