From lidar signals detected with a shot per shot differential absorption lidar instrument tuned for tropospheric ozone measurements and recording each individual return, we reconstruct histograms of their sampled values for each channel of our digitizers. The analysis of their shape permits the correction of our measurements for experimental biases. In particular, a negative correlation is found between the skew of the histograms and the intensity of the backscattered light. The skew comes from a tail at high sampled values, interpreted as due to a raise of the relative contribution to the signal of a signal-induced noise when this intensity diminishes. By fitting a Gaussian function to the histograms without considering their tails, we calculate average signals unbiased by the corresponding noise. This approach allows us to increase the range of our ozone profiles, up to as much as double it in some cases.
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http://dx.doi.org/10.1364/ao.36.006857 | DOI Listing |
BMC Geriatr
January 2025
Nursing School, Medical College of Hengyang, University of South China, Hengyang, China.
Background: China is experiencing an increasingly serious aging population. Cognitive function is an important factor and guarantee for the quality of life of older people. Therefore, to achieve healthy aging, this study aimed to examine the sequential multiple mediating effects of indoor ventilation frequency and cognitive function on anxiety and self-rated health in the Chinese older people population.
View Article and Find Full Text PDFSci Rep
January 2025
Brown University, Cognitive and Psychological Sciences, Providence, 02912, USA.
The existence of biases in visual perception and their impact on visually guided actions has long been a fundamental yet unresolved question. Evidence revealing perceptual or visuomotor biases has typically been disregarded because such biases in spatial judgments can often be attributed to experimental measurement confounds. To resolve this controversy, we leveraged the visuomotor system's adaptation mechanism - triggered only by a discrepancy between visual estimates and sensory feedback - to directly indicate whether systematic errors in perceptual and visuomotor spatial judgments exist.
View Article and Find Full Text PDFDiabetologia
January 2025
Kidney Transplantation Center, Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Aims/hypothesis: Diabetic kidney disease (DKD) features intrarenal inflammation, in which T cells play a part. Hypoxia-inducible factor-1α (HIF-1α), a key transcription factor regulating cellular responses to hypoxia, is reportedly involved in the course of inflammation. The role of HIF-1α in DKD has been investigated, but the conclusions are controversial so far.
View Article and Find Full Text PDFBMJ Open
January 2025
Interdisciplinary Research Center for Health Science, Sant'Anna School of Advanced Studies, Pisa, Italy
Objectives: Population ageing and the rise in chronic diseases place continual stress on healthcare systems. Scarce resources often impede equitable access to healthcare, particularly in rural areas, resulting in prolonged waiting times and heightened risks of morbidity and mortality. Telemedicine has emerged as a promising solution, offering remote and equitable care that could potentially bridge access gaps and enhance health outcomes.
View Article and Find Full Text PDFCogn Behav Ther
January 2025
Department of Psychology, Vanderbilt University, 312 Wilson Hall, 111 21st Avenue South, Nashville, TN 37240, USA.
Exposure therapy is an efficacious treatment for anxiety-related disorders. Yet, fear often returns after treatment. Occasional reinforcement, in which the feared stimulus is intermittently presented during extinction, increases safety learning and slows fear renewal in conditioning paradigms and analogue samples, but no studies to date have examined this strategy in clinical samples.
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