Identification of multiple-electrode stimulus patterns was evaluated in nine adult subjects, to assess the feasibility of providing additional speech information through the tactual display of an electrotactile speech processor. Absolute identification scores decreased from 97.8% for single electrodes, to 61.9% for electrode pairs, and, to 31.8% for electrode triplets. Although input information increased with paired-and triple-electrode stimuli, information transmission scores were not significantly increased for either electrode pairs (2.99 bits) or triplets (2.84 bits) as compared with single electrodes (2.84 bits). These results suggest that speech coding strategies using stimulus patterns of electrode pairs or triplets would provide little improvement beyond that found for the present single-electrode scheme. However, higher absolute identification scores (73.6%), and an increase in information transmission to 3.88 bits, were recorded for test stimuli containing all combinations of paired and single electrodes. Based on this finding, two stimulus sets using a restricted number of combinations of paired and single electrodes were evaluated. The two stimulus sets simulated the spatial patterns of paired and single electrodes arising from use of alternative speech coding schemes to increase consonant voicing information. Results for the two stimulus sets showed higher electrode identification scores (79.7% and 90.4%), as compared with paired-electrode stimuli. Although electrode identification score was not as high as for single electrodes, information transmission was increased to 3.31 bits for the VF2 stimulus set. Analysis of the responses also showed that scores for identification of simulated voicing information conveyed by the two stimulus sets were 99.4 and 90.4% correct.(ABSTRACT TRUNCATED AT 250 WORDS)
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Cell Rep
January 2025
Centre for Systems Neuroscience, University of Leicester, Leicester, UK; Hospital Del Mar Medical Research Institute (IMIM), Barcelona, Spain; Institució Catalana de Recerca I Estudis Avançats (ICREA), Barcelona, Spain; Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
In subjects implanted with intracranial electrodes, we use two different stories involving the same person (or place) to evaluate whether and to what extent context modulates human single-neuron responses. Nearly all neurons (97% during encoding and 100% during recall) initially responding to a person/place do not modulate their response with context. Likewise, nearly none (<1%) of the initially non-responsive neurons show conjunctive coding, responding to particular persons/places in a particular context during the tasks.
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January 2025
Nanjing Normal University, School of Chemistry and Materials Science, CHINA.
Metal hexacyanoferrates (HCFs), also known as Prussian blue analogues, are ideal cathodes for potassium-ion batteries (PIBs) due to their nontoxicity and cost-effectiveness. Nevertheless, obtaining metal HCF cathode materials with both long-term cycling stability and high rate performance remains a daunting challenge. In this study, we present mesoporous single-crystalline iron hexacyanoferrate (MSC-FeHCF) microspheres, featuring a single-crystalline structure that contains interconnected pores spanning the entire crystal lattice.
View Article and Find Full Text PDFJ Neural Eng
January 2025
Electrical and Computer Engineering Department, New York University, 370 Jay Street, Brooklyn, New York, New York, 10012-1126, UNITED STATES.
This study investigates speech decoding from neural signals captured by intracranial electrodes. Most prior works can only work with electrodes on a 2D grid (i.e.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry, State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong 999077, P. R. China.
Fe-N-C materials are emerging catalysts for replacing precious platinum in the oxygen reduction reaction (ORR) for renewable energy conversion. However, their potential is hindered by sluggish ORR kinetics, leading to a high overpotential and impeding efficient energy conversion. Using iron phthalocyanine (FePc) as a model catalyst, we elucidate how the local strain can enhance the ORR performance of Fe-N-Cs.
View Article and Find Full Text PDFNano Lett
January 2025
Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai-400005, India.
Predictive approaches and rules to connect and combine molecular circuit components are required to realize the potential of molecular electronics and develop miniaturized integrated circuits. To this end, we have recently demonstrated a bis(terpyridine)-based molecular breadboard with four conductance states formed by the superposition of five 2-5 ring circuits. Here, we develop a generic analytical/statistical model to describe break-junction data and use it to extract the conductance of the five embedded circuits in the bis-terpyridine-based molecular breadboard junction.
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