Super-sentinel chickens and detection of low-pathogenicity influenza virus.

Emerg Infect Dis

Department of Molecular and Cell Biology, University of Connecticut, U-3125, 75 North Eagleville Rd, Storrs, CT 06269, USA.

Published: October 2007

Chicken interferon-alpha administered perorally in drinking water acts on the oropharyngeal mucosal system as an adjuvant that causes chickens to rapidly seroconvert after natural infection by low-pathogenicity Influenza virus. These chickens, termed super sentinels, can serve as sensitive early detectors of clinically inapparent infections.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851500PMC
http://dx.doi.org/10.3201/eid1310.061552DOI Listing

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