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Examining Electronic Nicotine Delivery System (ENDS) Cue Reactivity Using a Remote Platform: Cigarette and ENDS Desire in Dual Users.
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University of Chicago, Department of Psychiatry and Behavioral Neuroscience, Chicago, IL.
Introduction: Prior research shows that in-person exposure to electronic nicotine delivery systems (ENDS) use increases desire for cigarettes and ENDS. However, less is known about the impact of cues delivered during remote interactions. This study extends previous in-person cue work by leveraging a remote confederate-delivered cue-delivery paradigm to evaluate the impact of dual nicotine vaping (vs.
View Article and Find Full Text PDFCurrent approaches in CRISPR-Cas systems for hereditary diseases.
Prog Mol Biol Transl Sci
January 2025
School of Health Sciences & Technology, UPES, Dehradun, Uttarakhand, India. Electronic address:
CRISPR-Cas technologies have drastically revolutionized genetic engineering and also dramatically changed the potential for treating inherited disorders. The potential to correct genetic mutations responsible for numerous hereditary disorders from single-gene disorders to complex polygenic diseases through precise DNA editing is feasible. The tactic now employed in CRISPR-Cas systems for treating inherited disorders is the usage of particular guide RNAs to target and edit disease-causing mutations in the patient's genome.
View Article and Find Full Text PDFDissociating the Roles of Alpha Oscillation Sub-Bands in Visual Working Memory.
Neuroimage
January 2025
Institute of Brain and Psychological Sciences, Sichuan Normal University, 610066 Sichuan, China; Brain and Cognitive Neuroscience Research Center, Liaoning Normal University, 116029 Liaoning, China. Electronic address:
Alpha oscillations play a critical role in visual working memory (VWM), but the specific contributions of lower and upper alpha sub-bands remain unclear. To address this, we employed a whole-field change detection paradigm to investigate how alpha power modulation and decoding accuracy differ between these sub-bands in response to varying set sizes and spatial extents of memory arrays. Our results revealed that lower alpha (8-9 Hz) exhibits widespread event-related desynchronization (ERD) during the early maintenance phase, which increases with set size and reflects attentional allocation to individual memory items.
View Article and Find Full Text PDFThe role of communication in environmental awareness according to circular economy stakeholders.
J Environ Manage
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Department of Audiovisual Communication and Advertising, Universidad Rey Juan Carlos. Camino Del Molino N° 5, Departmental Building 1, Office 234, Fuenlabrada, Madrid, 28943, Spain. Electronic address:
In order to make the transition from a linear to a circular economy, unprecedented measures are required from all social actors. Communication plays a fundamental role in this transition. The use of social marketing as an alternative to traditional communication models can promote the paradigm shift in order to increase communicative effectiveness.
View Article and Find Full Text PDFExtracellular vesicles: from intracellular trafficking molecules to fully fortified delivery vehicles for cancer therapeutics.
Nanoscale Adv
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Molecular Biology and Biochemistry Department, Faculty of Biotechnology, German International University (GIU) 11835 Cairo Egypt
Extracellular vesicles (EVs) are emerging as viable tools in cancer treatment due to their ability to carry a wide range of theranostic activities. This review summarizes different forms of EVs such as exosomes, microvesicles, apoptotic bodies, and oncosomes. It also sheds the light onto isolation methodologies, characterization techniques and therapeutic applications of all discussed EVs.
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