[Effect of baicalin on in vivo anti-virus].

Zhongguo Zhong Yao Za Zhi

Pharmacy department, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China.

Published: November 2007

AI Article Synopsis

  • - The study investigates the antiviral effects of baicalin on mice infected with the influenza virus (A/FM/1/47) to determine its protective and healing capabilities.
  • - One group of mice received baicalin two days before infection, while another group was treated one day after infection, allowing for a comparison of baicalin's effects.
  • - Results showed that baicalin significantly increased survival time, eliminated the virus in the lungs, reduced infection severity, and improved lung health in the infected mice.

Article Abstract

Objective: This study is about the in vivo antivirus effect of baicalin.

Method: Adopting in vivo experiment, we administered one group of mice 2 days before infected with influenza virus (A/FM/1/47) , while administer the other group with baicalin one day after infected, to observe the effect of baicalin in protecting and curing mice against influenza virus.

Result: Baicalin can obviously prolong the survival time of mice infected with influenza virus (A/FM/1/47) (P <0.01), eliminate the influenza virus in lung, reduce the hemagglutination tite and infectivity in pulmo, and reverse mice's pneumonic pathological changes.

Conclusion: Baicalin can obviously counteract influenza virus.

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