Introduction: Tobacco use is an important risk factor for advanced histopathological findings on edentulous alveolar ridge mucosa. The aim of this study was to examine the effects of smoking on histopathological findings on edentulous alveolar ridge mucosa.
Material And Methods: The experimental group consisted of 48 patients (29 smokers and 19 nonsmokers). The mean age of smokers was 42.6 and of nonsmokers 48.7 years. The anamnesis included the following data: age, sex, diseases and toxic habits--cigarette smoking. Biopsy samples were taken from the edentulous alveolar ridge mucosa without gross signs of symptoms.
Results: The mean number of cigarettes smoked per day was 11.5 +/- 7. The results of chi2 test proved that there were no statistically significant differences (p > 0.05) in histopathological findings on the alveolar ridge mucosa. The mean duration of smoking was 12.7 +/- 5 years. Hyperkeratosis was established in 76.92% of smokers who smoked longer than 15 years. The mean age at which smokers began smoking was 27.3 +/- 8 years and there were no statistically significant differences in histopathological findings on the alveolar ridge mucosa correlated with the beginning of smoking.
Conclusion: On the basis of our research we conclude that smokers who have been smoking for 15 years are at risk for developing histopathological changes of the alveolar ridge mucosa, but there were no statistically significant differences in histopathological findings on the alveolar ridge mucosa correlated with the number of cigarettes per day and the beginning of smoking.
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http://dx.doi.org/10.2298/mpns0502023m | DOI Listing |
Am J Orthod Dentofacial Orthop
January 2025
Department of Orthodontics, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic; Department of Dentistry, First Faculty of Medicine, Charles University and the General University Hospital, Prague, Czech Republic. Electronic address:
Introduction: The primary aim of this study was to assess the amount and long-term stability of orthodontically created bone in patients with agenesis of maxillary lateral incisors after canine distalization. The secondary aim was to explore the impact of patient age on the process of alveolar bone resorption.
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J Korean Assoc Oral Maxillofac Surg
December 2024
Department of Prosthodontics, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.
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View Article and Find Full Text PDFBMC Oral Health
December 2024
College of Dental Medicine, QU Health, Qatar University, P.O. Box: 2713, Doha, Qatar.
Background: The collum angle, tooth dimensions, root length, and alveolar bone thickness have a significant impact on orthodontic diagnosis and treatment planning. The boundaries of orthodontic tooth movement are determined by alveolar bone thickness and dimensions while the collum angle determines the appropriate positioning of the root relative to the cortical plate. This study aimed to compare the collum angle, crown dimensions, root length, and alveolar bone thickness of the upper and lower incisors, canines, and premolars in subjects with varying anteroposterior relationships.
View Article and Find Full Text PDFBMC Oral Health
December 2024
Department of Orthodontics, Central Laboratory, Hospital for Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Peking University School, 22th Zhongguancun South Ave, Beijing, 100081, China.
Background: Orthodontic tooth movement (OTM) relies on the remodeling of periodontal tissues, including the periodontal ligament (PDL) and alveolar bone. Collagen remodeling plays a crucial role during this process, allowing for the necessary changes in the PDL's structure and function. Endo180, an urokinase plasminogen activator receptor-associated protein, is a transmembrane receptor regulated collagen remodeling.
View Article and Find Full Text PDFJ Chem Inf Model
December 2024
School of Pharmacy, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Pulmonary fibrosis is excessive scarring of the lung tissues. Transforming growth factor-beta (TGF-β) has been implicated in pulmonary fibrosis due to its ability to induce the epithelial-to-mesenchymal transition (EMT) and promote epithelial cell migration. Cyclin-dependent kinase 8 (CDK8) can mediate the TGF-β signaling pathways and could function as an alternative therapeutic target for treating pulmonary fibrosis.
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