[Pre- and intraoperative ultrasound imaging in neurosurgery].

Advanced applications of ultrasound in neurosurgery have been evaluated in two projects of the Ruhr Center of Excellence for Medical Engineering (KMR), Bochum, Germany. Engineers, neurologists, and neurosurgeons are cooperating within an interdisciplinary project structure, in order to practically approach neurosurgical problems by elaborating novel ultrasound-based technologies. On one hand, procedures have been implemented for an ultrasound-based registration of bone structures, applicable, amongst others, to the high-accuracy navigation of pedicle screws. On the other hand, concepts have been developed regarding a pre- and intraoperative application of ultrasound contrast agents for the detection of cerebral tumors and for the monitoring of surgery. In this article, both projects are discussed on the basis of the results obtained thus far and, furthermore, potentials of these concepts are presented that may complement or extend the scopes of the neurosurgical practice.