We complement the study of the asymptotic behaviour of the dynamical threshold neuron model with delay, introduced by Gopalsamy and Leung, by providing a description of the dynamics of the system in the remaining parameters range. We characterize the regions of "harmless" delays and those in which delay-induced oscillations appear.
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http://dx.doi.org/10.1109/72.655047 | DOI Listing |
PLoS Comput Biol
January 2025
College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou, People's Republic of China.
Gaussia Luciferase (GLuc) is a renowned reporter protein that can catalyze the oxidation of coelenterazine (CTZ) and emit a bright light signal. GLuc comprises two consecutive repeats that form the enzyme body and a central putative catalytic cavity. However, deleting the C-terminal repeat only limited reduces the activity (over 30% residual luminescence intensity detectable), despite being a key part of the cavity.
View Article and Find Full Text PDFKidney Med
November 2024
Division of Geriatrics and Extended Care, Edward Hines, Jr. VA Hospital, Hines, IL.
Rationale & Objective: Engaging patients with advanced chronic kidney disease (CKD) in goals of care (GOC) conversations is essential to align life-sustaining treatments with patient preferences. This pilot study described the feasibility of engaging older Veterans with advanced CKD in GOC conversations via telehealth by (1) comparing patient characteristics, including life-sustaining treatment note completion rates and preferences by visit modality, and (2) exploring Veteran and clinician perspectives surrounding telehealth GOC conversations.
Study Design: Mixed-method convergent design including a prospective, quantitative observational cohort analysis (n = 40) and qualitative, semi-structured interviews with 4 clinicians and 11 Veterans.
Behav Res Methods
January 2025
Department of Data Analysis, Ghent University, Henri Dunantlaan 1, 9000, Ghent, Belgium.
Model estimation for SEM analyses in commonly used software typically involves iterative optimization procedures, which can lead to nonconvergence issues. In this paper, we propose using random starting values as an alternative to the current default strategies. By drawing from uniform distributions within data-driven lower and upper bounds (see De Jonckere et al.
View Article and Find Full Text PDFInt J Mol Med
February 2025
Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang 627-706, Republic of Korea.
Strabismus
October 2024
Department of Ophthalmology, The Royal Free Hospital, London, UK.
Although there are guidance tables in the literature on surgical dosage for primary medial rectus resection-lateral rectus recession surgery, there is a lack of consensus on the surgical gains in medial rectus re-advancement (MRR) for the management of consecutive exotropia. We compared the surgical outcomes of primary medial rectus resection-lateral recession (RR) surgery, to MRR in patients with consecutive exotropia. Retrospective, electronic note review of consecutive patients undergoing primary RR surgery for basic exotropia (RR group), convergence insufficiency-type exotropia, and divergence excess, and consecutive patients undergoing MRR with or without lateral rectus recession (MRR group) for consecutive exotropia in a teaching university hospital.
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