Postnatal investigation of fetal renal disease.

Semin Fetal Neonatal Med

Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, UK.

Published: June 2008

AI Article Synopsis

  • Routine prenatal ultrasounds have improved the detection of fetal renal tract abnormalities, leading to more asymptomatic infants becoming patients for pediatric consultations.
  • The urgency for follow-up imaging varies based on the specific abnormality, with conditions like bilateral hydronephrosis and posterior urethral valves prioritized for evaluation and treatment.
  • Ultrasound is the primary imaging method used after birth, but magnetic resonance urography may become increasingly important for assessing more complicated cases in the future.

Article Abstract

Following the introduction of routine prenatal scanning, and more recently detailed anomaly scans, antenatal ultrasound (US) diagnosis of fetal renal tract abnormalities has become well established. Prenatal detection has resulted in a group of asymptomatic infants becoming patients in the last two decades. These infants are referred for paediatric (general, urological and nephrological) consultations, radiological imaging and monitoring. The urgency with which to undertake imaging depends on the suspected antenatal diagnosis and clinical scenario, with bilateral hydronephrosis, posterior urethral valves and complicated duplex systems taking a high priority. Treatment is mainly preventive and relies on close follow-up and timely intervention. US remains the main imaging modality of choice postnatally; together with nuclear medicine, it gives a powerful combination of both anatomy and function. However, magnetic resonance urography may have increasing importance in becoming the investigation of choice of the future for more complex cases.

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Source
http://dx.doi.org/10.1016/j.siny.2007.10.008DOI Listing

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