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Cutaneous Angiosarcoma With Scalp and Skull Infiltration: A Comprehensive Case Report and Treatment Considerations.
J Craniofac Surg
December 2024
Division of Neurosurgery, Department of Surgery.
Cutaneous angiosarcoma is a rare and aggressive malignancy originating from endothelial cells lining blood vessels in the skin. The authors present a comprehensive case report of cutaneous angiosarcoma with infiltration of the scalp and skull, with an abnormal presentation highlighting the clinical features, diagnostic challenges, treatment and surgical strategies, and outcomes. The case underscores the complexity of managing this aggressive disease involving critical anatomical structures and emphasizes the need for a multidisciplinary approach to optimal patient care.
View Article and Find Full Text PDFOff-label dermatologic uses of IL-23 inhibitors.
J Dermatolog Treat
December 2024
Department of Dermatology, University of Illinois College of Medicine, Chicago, IL, USA.
Background: While IL-23 inhibitors, which include guselkumab, tildrakizumab, and risankizumab, are currently FDA-approved solely for the treatment of psoriasis, several other inflammatory skin conditions have been associated with elevated IL-23 levels. The purpose of this review is to summarize and interpret the literature surrounding the off-label uses of IL-23 inhibitors in dermatologic practice.
Methods: We conducted searches on PubMed and for clinical trials, observational studies, case series, and case reports assessing use of the three IL-23 inhibitors for non-psoriatic dermatologic conditions.
Prolonged subcutaneous swelling after head trauma: A rare but serious case of angiosarcoma of the scalp that should be known by dermatologists as well as by elderly-healthcare professionals.
Geriatr Gerontol Int
November 2024
Department of Radiology, Akita University Graduate School of Medicine, Akita, Japan.
Angiosarcoma of the Scalp Mimicking an Inflammatory Scarring Alopecia and Diagnosed on Horizontal Histologic Sections.
J Cutan Pathol
November 2024
Department of Pathology and Dermatology, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
While most forms of alopecia neoplastica are attributable to cutaneous metastases from visceral primary malignancies, rarely a diffuse primary skin cancer may present as alopecia. Herein, we present a case of angiosarcoma which clinically mimicked an inflammatory alopecia and was diagnosed by examination of alopecia-protocol horizontal histologic sections. A 72-year-old female presented to her dermatologist with a chief complaint of hair loss and pruritus.
View Article and Find Full Text PDFCutaneous angiosarcoma masquerading as photodermatitis: a case report.
Acta Dermatovenerol Alp Pannonica Adriat
December 2024
Department of Radiology, King Abdulaziz Hospital, Jeddah, Saudi Arabia.
Article Synopsis
- - Angiosarcoma (AS) is a rare, aggressive cancer that starts in endothelial cells, often appearing as skin lesions on the head and neck, making it hard to diagnose due to its variable signs.
- - An 87-year-old woman had an asymptomatic neck nodule that worsened and was initially misdiagnosed as cellulitis; it did not respond to typical treatments, highlighting the challenges of identifying AS.
- - The prognosis for AS is poor, with a 5-year survival rate of around 35%, and treatment often involves a mix of surgery, radiation, and chemotherapy, tailored to the individual's case.
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