1. Lymphocytes.

J Allergy Clin Immunol

University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

Published: February 2008

Lymphocytes are white blood cells uniform in appearance but varied in function and include T, B, and natural killer cells. These cells are responsible for antibody production, direct cell-mediated killing of virus-infected and tumor cells, and regulation of the immune response. Advances in immunology have led to the characterization of newly appreciated effector populations such as IL-17-producing T cells, T cells with regulatory function, and natural killer T cells, thus revising established paradigms. This chapter provides an overview of the major lymphocyte populations with emphasis on their development, distinguishing characteristics, and functions.

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http://dx.doi.org/10.1016/j.jaci.2007.06.016DOI Listing

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