This paper describes an approach based on evolutionary algorithms, hierarchical decision rules (HIDER), for learning rules in continuous and discrete domains. The algorithm produces a hierarchical set of rules, that is, the rules are sequentially obtained and must therefore be tried until one is found whose conditions are satisfied. Thus, the number of rules may be reduced because the rules could be inside of one another. The evolutionary algorithm uses both real and binary coding for the individuals of the population. We tested our system on real data from the UCI repository, and the results of a ten-fold cross-validation are compared to C4.5s, C4.5Rules, See5s, and See5Rules. The experiments show that HIDER works well in practice.
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http://dx.doi.org/10.1109/TSMCB.2002.805696 | DOI Listing |
Adv Mater
December 2024
Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Department of Chemistry, Fudan University, Shanghai, 200032, China.
While tumor organoids have revolutionized cancer research by recapitulating the cellular architecture and behaviors of real tumors in vitro, their lack of functional vasculature hinders their attainment of full physiological capabilities. Current efforts to vascularize organoids are struggling to achieve well-defined vascular networks, mimicking the intricate hierarchy observed in vivo, which restricts the physiological relevance particularly for studying tumor progression and response to therapies targeting the tumor vasculature. An innovative vascularized patient-derived tumor organoids (PDTOs)-on-a-chip with hierarchical, tumor-specific microvasculature is presented, providing a versatile platform to explore tumor-vascular dynamics and antivascular drug efficacy.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Beijing Key Laboratory for HIV/AIDS Research, Sino-French Joint Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing, China.
Human immunodeficiency Virus (HIV) and () co-infection presents a significant public health challenge worldwide. Comprehensive assessment of the immune response in HIV/ co-infection is complex and challenging. CD8T cells play a pivotal role in the adaptive immune response to both HIV and .
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December 2024
Department of Research, Innlandet Hospital Trust, Brumunddal, Norway.
Objective: We aimed to explore how specific cognitive processes, such as attention and executive functions, account for variance in decision-making measured by Iowa Gambling Task (IGT) performance among individuals with schizophrenia spectrum disorders.
Methods: Adults ( = 65, = 25.4) with schizophrenia spectrum disorders participating in a clinical trial (registered at clinicaltrials.
Asia Pac J Oncol Nurs
December 2025
Department of Oncology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Objective: This study aimed to explore hospice caregivers' downward referral decision-making experiences and barriers under the triadic linkage model in China and to analyze the deeper social dynamics of hospice referral choices.
Methods: Semi-structured interviews were conducted with caregivers handling hospice referrals from two primary hospice agencies in Nanjing, China. The themes were analyzed and summarized using the Colaizzi 7-step analysis.
PLoS One
December 2024
Shanghai Fire Research Institute Of MEM, Shanghai, China.
The fire station location has essential theoretical and practical values, not only in terms of maintaining the safety of life and property, but also enriching the optimization theory of site selection problems. To study the multi-objective siting problem of fire stations, we firstly divided demand areas and fire stations into three levels to form a comprehensive hierarchical emergency coverage network covering fire risk areas. Secondly, the nodes of the original location of the fire station were added to the set of nodes of the planned construction of the fire station.
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