AI Article Synopsis
- * Researchers extracted mRNA from CD4(+) lymphocyte samples, which were then labeled and analyzed using microarrays to identify gene expression patterns.
- * The results revealed 55 genes with differential expression between RF(+) and RF(-) patients, indicating that these genes are connected to immune responses in rheumatoid arthritis.
Article Abstract
Aim: To explore the differences of the gene expression of CD4(+) lymphocytes between the RF(+) and RF(-) patients with rheumatoid arthritis.
Methods: mRNA of all the CD4(+) lymphocytes samples were extracted and identified. Then they were labeled and hybridized to microarrays.
Results: Hierarchical clustering analysis showed there were 55 differential expression genes between the RF(+) and RF(-) patients with rheumatoid arthritis.
Conclusion: There are differential expression genes between the RF(+) and RF(-) patients and these genes are related to immunoresponse.
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