We examine the surface morphological evolution of a conducting crystalline solid under the simultaneous action of an electric field and mechanical stress based on a fully nonlinear model and combining linear stability theory with self-consistent dynamical simulations. We demonstrate that electric current, through surface electromigration, can stabilize the surface morphology of the stressed solid against cracklike surface instabilities. The results also have more general implications for the morphological response of solid surfaces under the simultaneous action of multiple external forces.
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http://dx.doi.org/10.1103/PhysRevLett.100.036106 | DOI Listing |
In Vivo
December 2024
Department of Veterinary Medicine, Yanbian University, Yanji, P.R. China;
Background/aim: This study aimed to investigate the safety and efficacy of deferoxamine (DFO) pretreated feline adipose tissue derived mesenchymal stem cells (fATMSCs) for the treatment of inflammatory disorders.
Materials And Methods: fATMSCs were isolated from feline adipose tissue and characterized using flow cytometry for surface marker expression and differentiation assays for adipogenic, osteogenic, and chondrogenic lineages. Different concentrations of DFO were used to evaluate its impact on fATMSC activity.
Anticancer Res
January 2025
Section of Endocrinology, Diabetes, Nutrition and Weight Management, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, U.S.A.;
Background/aim: Obese individuals often exhibit vitamin D deficiency, potentially due to sequestration in fat cells. Little is known about how vitamin D enters adipocytes and associates with the intracellular lipid droplet.
Materials And Methods: Newly differentiated human and mouse (3T3-L1) adipocytes and primary mouse adipocytes were treated with vitamin D covalently linked to green fluorescent BODIPY (VitD-B) or Green BODIPY (GB) as control.
Anticancer Res
January 2025
Eisai Inc., Cambridge, MA, U.S.A.
Background/aim: Preclinical studies were undertaken to investigate whether eribulin's known cytotoxic antimitotic effects are characterized by immunogenic cell death (ICD) as assessed by three established ICD biomarkers: extracellular released ATP, released HMGB1 and cell surface calreticulin.
Materials And Methods: Using BT-549, Hs578T and MCF-7 breast cancer cell lines, antiproliferative IC's of eribulin, five other microtubule targeting agents (MTAs; ER-076349, vinblastine, vinorelbine, paclitaxel, docetaxel) and three DNA damaging agents (DDAs; doxorubicin, cisplatin, oxaliplatin) were determined.
Results: Treatment of cells with 10×IC concentrations of all drugs in serum-free media resulted in time-dependent induction of cytotoxicity over DMSO controls.
Int J Biol Macromol
December 2024
Department of Chemistry, University of Delhi-110007, New Delhi, India.
Wastewater contamination by organic dyes, especially Rhodamine B (RhB), possess a significant environmental challenge. This study explores a novel bio sorbent for the removal of RhB dye from contaminated water, using chitosan trisodium citrate-modified magnetic nanoparticles (Fe₃O₄@CSTSC@PANI) coated with polyaniline. The nanocomposite was characterized by FT-IR, XRD, HRTEM, SEM, BET surface analysis.
View Article and Find Full Text PDFPLoS One
December 2024
Faculty of Science, Department of Biosciences, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia.
Bacterial cellulose (BC) is a novel biocompatible polymeric biomaterial with a wide range of biomedical uses, like tissue engineering (TE) scaffolds, wound dressings, and drug delivery. Although BC lacks good cell adhesion due to limited functionality, its tunable surface chemistry still holds promise. Here, hydroxyapatite (HA) was incorporated into a citrate-modified BC (MBC) using the biomimetic synthesis in simulated body fluid (SBF).
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