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December 2024
NanoMag Lab, Department of Applied Physics, Faculty of Science University of Granada, Planta-1, Edificio I+D Josefina Castro, Av. de Madrid, 28, 18012 Granada, Spain.
Local hyperthermia is gaining considerable interest due to its promising antitumor effects. In this context, dual magneto-photothermal cancer therapy holds great promise. For this purpose, the use of nanomaterials has been proposed.
View Article and Find Full Text PDFSolution biophysics identifies lipid nanoparticle non-sphericity, polydispersity, and dependence on internal ordering for efficacious mRNA delivery.
bioRxiv
December 2024
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lipid nanoparticles (LNPs) are the most advanced delivery system currently available for RNA therapeutics. Their development has accelerated since the success of Patisiran, the first siRNA-LNP therapeutic, and the mRNA vaccines that emerged during the COVID-19 pandemic. Designing LNPs with specific targeting, high potency, and minimal side effects is crucial for their successful clinical use.
View Article and Find Full Text PDFAsymmetric Microgels with Tunable Morphologies by Assembly-Guided Polymerization of Liquid Crystalline Monomers.
Small
January 2025
Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Article Synopsis
- Understanding microgel morphology is key for enhancing their functions in various applications, but traditional methods are often limited and low in efficiency.
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Ice crystal particles play an important role in the study of cloud resolution, climate models, and radiative forcing. During the melting process, significant changes occur in the microphysical properties of ice crystal particles, such as the ice phase state, morphology, and mixing state. This process further affects the scattering and radiation characteristics properties of ice crystal particles.
View Article and Find Full Text PDFAdvanced scattering techniques for characterisation of complex nanoparticles in solution.
Adv Colloid Interface Sci
December 2024
School of Health and Biomedical Sciences, RMIT University, Melbourne, Australia; Department of Chemistry and Biotechnology, School of Science, Computing and Engineering Technologies, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Nanoparticles are vital to a broad range of applications including commercial formulations, sensing and advanced material synthesis. Nanoparticles can come in a variety of shapes including cubes, polyhedra, rods, and prisms, and recent literature has demonstrated the importance of nanoparticle shape to downstream function (such as cellular uptake). While researchers routinely characterise nanoparticle shape using electron microscopy techniques, this generally requires drying of the samples.
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