Overall 438 children with extrahepatic portal hypertension underwent surgical treatment. Portal-systemic bypass was performed at 383 patients, meso-portal bypass -- at 56. These surgical procedures were effective at 96.4% cases. All the children with bleeding recurrences were operated repeatedly. Meso-portal bypass not only prevents risk of bleeding but also reconstruct normal anatomy and physiology of portal system.
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S Afr Med J
November 2017
Department of Paediatric Surgery, University of the Witwatersrand, Johannesburg, South Africa.
Background: Portal hypertension is a common and potentially devastating condition in children. Notwithstanding advances in the nonsurgical management of portal hypertension, surgery remains an important treatment modality in select patients. We report here on our experience in the past 12 years.
View Article and Find Full Text PDFExpert Rev Gastroenterol Hepatol
May 2015
Liver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, UK.
Portal hypertension is one of the most serious complications of childhood liver disease, and variceal bleeding is the most feared complication. Most portal hypertension results from cirrhosis but extra hepatic portal vein obstruction is the single commonest cause. Upper gastrointestinal endoscopy endoscopy remains necessary to diagnose gastro-esophageal varices.
View Article and Find Full Text PDFPediatr Radiol
December 2010
Department of Radiology, Cliniques Universitaires St. Luc, Avenue Hippocrate 10, 1200, Brussels, Belgium.
Post-transplant children are regularly followed by colour Doppler US exam. Liver parenchyma, biliary tract and portal, subhepatic and arterial vascularisation are checked. We observed a post-transplant child with spontaneous meso-portal bypass after portal vein thrombosis (PVT).
View Article and Find Full Text PDFOverall 438 children with extrahepatic portal hypertension underwent surgical treatment. Portal-systemic bypass was performed at 383 patients, meso-portal bypass -- at 56. These surgical procedures were effective at 96.
View Article and Find Full Text PDFJ Pediatr Surg
August 2003
Liver Unit, Birmingham Children Hospital, Birmingham, England UK.
Background/purpose: In children with portal vein (PV) thrombosis, hepatopetal portal flow can be restored by an innovative surgical procedure, the meso-portal-bypass (MPB), if the umbilical portion of the intrahepatic left PV and the superior mesenteric vein are patent. This is associated with resolution of symptoms related to extrahepatic portal hypertension (EHPH). However, no data are available yet on intrahepatic hemodynamic changes after MPB.
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