AI Article Synopsis
- A hypothesis suggests that a patient’s eye color may predict their risk of hearing loss from cis-platin treatment, linking melanin levels in both eyes and inner ears.
- Patients with dark eyes, having more melanin, could experience more hearing damage compared to those with light-colored eyes.
- The investigation not only confirmed this link but also highlighted potential damage to the auditory nerve due to the treatment.
Article Abstract
The following hypothesis is presented: that the susceptibility of an individual patient to hearing loss as a result of cis-platinum administration can be predicted on the basis of eye colour. The rationale is that the melanin content of the inner ears is related to that of the eyes; dark eyes contain more melanin than light-coloured eyes; and melanin causes the accumulation of the ototoxic drug within the inner ear. Hence those with dark eyes will suffer greater damage to the hearing than those with pale eyes. An investigation that confirmed this hypothesis is reported. In addition to cochlear damage there is a significant likelihood of damage to the auditory nerve as a result of the treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1017/s0022215100114689 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Establishing an objective quantitative method for assessing the severity of plus disease in retinopathy of prematurity.
Graefes Arch Clin Exp Ophthalmol
January 2025
College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Background: To establish an objective method for assessing plus disease severity in retinopathy of prematurity.
Methods: Six images of plus diseases that were color-coded according to severity and published in the International Classification of Retinopathy of Prematurity, Third Edition (ICROP3) were analyzed. These images were individually processed, and the best-fit curve and vessel course in zone I were obtained using ImageJ software.
Diverse neuronal activity patterns contribute to the control of distraction in the prefrontal and parietal cortex.
PLoS Biol
January 2025
Institute of Applied and Computational Mathematics, Foundation for Research and Technology Hellas, Heraklion, Crete, Greece.
Goal-directed behavior requires the effective suppression of distractions to focus on the task at hand. Although experimental evidence suggests that brain areas in the prefrontal and parietal lobe contribute to the selection of task-relevant and the suppression of task-irrelevant stimuli, how conspicuous distractors are encoded and effectively ignored remains poorly understood. We recorded neuronal responses from 2 regions in the prefrontal and parietal cortex of macaques, the frontal eye fields (FEFs) and the lateral intraparietal (LIP) area, during a visual search task, in the presence and absence of a salient distractor.
View Article and Find Full Text PDFEmpowering Communication in Medicine: A Workshop Approach to Improve Presentation Skills for Ear, Nose, and Throat Specialists.
Cureus
December 2024
Department of Otolaryngology - Head and Neck Surgery, University of Fukui, Yoshida, JPN.
Introduction Effective communication is crucial for healthcare professionals, impacting patient care and interdisciplinary collaboration. However, medical education often lacks structured training in communication and presentation techniques. Herein, we evaluate the efficacy of structured workshops aimed at enhancing presentation skills among ear, nose, and throat (ENT) doctors through training in visual material design and concise verbal communication, including elevator pitches.
View Article and Find Full Text PDFCutaneous Anthrax: What is the Hallmark?
Acta Med Indones
October 2024
Division of Tropical and Infection Diseases, Department of Internal Medicine, Medical Faculty of Universitas Sebelas Maret - Moewardi Hospital, Surakarta, Indonesia.
A 71-year-old man complained of a blackish wound under his left eye, which began with fever and reddish spots after helping to slaughter a cow and cut its meat. The fever occured especially in the afternoon to evening, and is not accompanied by chills and sweating. On day 4 of fever onset, the fever diminished and the spots progressively widened with swelling.
View Article and Find Full Text PDFA shikimic acid derived carbon dots (SACNDs-FITC) for multi-modal detection and removal of Hg: Probe design, sensing performance, and applications in food analysis.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Key Laboratory of Life-Organic Analysis of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165, China.
The first shikimic acid derived fluorescent carbon dots (SACNDs-FITC) for multi-modal detection and simultaneous removal of Hg is revealed. The fluorescence of SACNDs-FITC centered at 520 nm can be selectively quenched by Hg, while the emission centered at 420 nm remains constant which can be used for self-calibration. Naked-eye distinguishable color change from yellow to colourless under daylight and from green to blue under UV light could be observed for SACNDs-FITC in the real-time detection of Hg.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!