We determine phenotypic susceptibility of human immunodeficiency virus type 2 (HIV-2) isolates to amprenavir, atazanavir, darunavir, indinavir, lopinavir, nelfinavir, saquinavir, and tipranavir. Saquinavir, lopinavir, and darunavir are potent against wild-type HIV-2 isolates and should be preferred as first-line options for HIV-2-infected patients. Other protease inhibitors are less active against HIV-2 than against HIV-1.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292533 | PMC |
| http://dx.doi.org/10.1128/AAC.01284-07 | DOI Listing |
Publication Analysis
Top Keywords
phenotypic susceptibility
8
susceptibility human
8
human immunodeficiency
8
immunodeficiency virus
8
virus type
8
protease inhibitors
8
hiv-2 isolates
8
vitro phenotypic
4
type clinical
4
clinical isolates
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!