Genital prolapses usually occurs in the post-menopausal period. Patients under 50 years of age with genital prolapse represent about 25% of candidates for surgical reconstruction in our center. Some of these patients wish to conserve their child-bearing potential and most want to be able to have a normal sex life. Five per cent of these women, all under 35, have isolated hysterocele and a hypertrophic uterine cervix. This article focuses on the etiology, prevention and new surgical treatments of genital prolapse in young women. Etiologies include late age at first pregnancy, chronic lung disease, and perineal damage during delivery. Connective-tissue and collagen disorders predominate before 35 years of age. New surgical procedures include vaginal repair with synthetic mesh. Laparoscopic sacropexy is still the gold standard. Prevention includes non traumatic delivery (Caeseran section), while pelvic floor exercises are mandatory after vaginal delivery.
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Colorectal Dis
January 2025
Department of Anorectal Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Inflamm Bowel Dis
January 2025
Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.
Background: Inflammatory bowel disease (IBD) is often diagnosed in young adults, and therefore frequently coincides with pregnancy. Patients may require surgery that includes (temporary) stoma placement. Literature on the occurrence of stoma-complications during pregnancy and the effect on pregnancy outcomes is limited.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, 730050, China.
Implantation of a mesh loaded with mesenchymal stem cells (MSCs) is a common approach for the treatment of pelvic organ prolapse (POP). The mesh provides effective support to pelvic floor, enhancing muscle contraction of pelvic organs while reducing inflammation. In this study, a fully degradable mesh is designed for the treatment of POP, utilizing MSCs stimulated by a galvanic battery-powered electric field.
View Article and Find Full Text PDFCureus
November 2024
Cardiology, Mount Sinai West Hospital, New York, USA.
The mechanism and severity of mitral valve (MV) regurgitation (MR) play a critical role in guiding treatment decisions. Transthoracic echocardiography (TTE) is the primary diagnostic modality for evaluating MV disease. Discordant findings on TTE can be further quantified through transesophageal echocardiography (TEE).
View Article and Find Full Text PDFInt J Womens Health
December 2024
Department of Urology, Università "la Sapienza", ICOT, Latina, Italy.
Purpose: Surgical repair is considered the mainstay of genital prolapse management. Several procedures are available both by vaginal and abdominal route, with and without mesh augmentation. The Italian UroGynecology Association (AIUG) promoted this survey with the aim of evaluating current variations in the surgical management of various types of prolapse in different clinical settings and to compare practice amongst practitioners working in high- and medium/low-volume centers.
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