A consistent theme in the literature on interventions for orphans and vulnerable children is the need for community-based care. However, a number of socio-cultural factors may impede community response. In this study, mixed methods are used to elucidate community-level barriers to care for orphans and vulnerable youth in Rwanda. Data from a large survey of youth heads of household on perceptions of marginalization from the community and the factors predicting that marginalization are considered in light of additional data from a survey of adults who volunteered to mentor these youth and focus groups with both community adults and youth heads of household. Results highlight how orphans' impoverished condition, cause of parents' death, and community perceptions of orphan behavior play a role in the marginalization of orphaned youth in Rwanda. Evidence is also offered to show that targeting humanitarian assistance to vulnerable youth may inadvertently lessen the level of community support they receive and contribute to their marginalization. The implications of these data for community-based program approaches are discussed.
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http://dx.doi.org/10.1016/j.socscimed.2007.12.001 | DOI Listing |
G3 (Bethesda)
January 2025
Department of Soil and Crop Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Orphan crops serve as essential resources for both nutrition and income in local communities and offer potential solutions to the challenges of food security and climate vulnerability. Tef [Eragrostis tef (Zucc.)], a small-grained allotetraploid, C4 cereal mainly cultivated in Ethiopia, stands out for its adaptability to marginal conditions and high nutritional value, which holds both local and global promise.
View Article and Find Full Text PDFTrop Med Health
January 2025
Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Background: Childhood is a crucial period that shapes a person's growth and development. For orphans, a lack of familial support affects their upbringing, making orphanages crucial for care. Children living in orphanage centers are vulnerable to several conditions, including dermatological disorders, due to factors such as malnutrition, overcrowding, and poor hygiene.
View Article and Find Full Text PDFBMJ Open
January 2025
Reproductive Health Study Group, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Objectives: Childhood violence exposure is a public health concern that has long-term impacts on health and well-being. This study aims to identify the factors contributing to childhood violence exposure.
Design: This study conducted a secondary data analysis to examine childhood violence exposure.
AIDS
January 2025
Pediatric Hematology and Immunology Department, Necker Hospital, GHU APHP.Centre - Université de Paris, Paris, France.
Objective: Most data published on adolescents living with HIV (ALH) have been collected before the large diffusion of second-generation integrase strand transfer inhibitors (INSTI) among the pediatric population. We analyzed the nationwide ANRS-MIE CO10 Pediatric cohort to assess the changes over time in health and social outcomes of French ALH.
Design: The cohort enrolled children born in France since 1985 and, from 2005, children diagnosed with HIV at ≤13 years, including those born abroad if antiretroviral-naive at first medical care in France.
Cell Death Dis
January 2025
Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, USA.
The orphan nuclear receptor NR2E3 has emerged as a potential tumor suppressor, yet its precise mechanisms in tumorigenesis require further investigation. Here, we demonstrate that the full-length protein isoform of NR2E3 instead of its short isoform activates wild-type p53 and is capable of rescuing certain p53 mutations in various cancer cell lines. Importantly, we observe a higher frequency of NR2E3 mutations in three solid tumors compared to the reference population, highlighting its potential significance in tumorigenesis.
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