Mapping high-dimensional data in a low-dimensional space, for example, for visualization, is a problem of increasingly major concern in data analysis. This paper presents data-driven high-dimensional scaling (DD-HDS), a nonlinear mapping method that follows the line of multidimensional scaling (MDS) approach, based on the preservation of distances between pairs of data. It improves the performance of existing competitors with respect to the representation of high-dimensional data, in two ways. It introduces (1) a specific weighting of distances between data taking into account the concentration of measure phenomenon and (2) a symmetric handling of short distances in the original and output spaces, avoiding false neighbor representations while still allowing some necessary tears in the original distribution. More precisely, the weighting is set according to the effective distribution of distances in the data set, with the exception of a single user-defined parameter setting the tradeoff between local neighborhood preservation and global mapping. The optimization of the stress criterion designed for the mapping is realized by "force-directed placement" (FDP). The mappings of low- and high-dimensional data sets are presented as illustrations of the features and advantages of the proposed algorithm. The weighting function specific to high-dimensional data and the symmetric handling of short distances can be easily incorporated in most distance preservation-based nonlinear dimensionality reduction methods.
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http://dx.doi.org/10.1109/tnn.2007.891682 | DOI Listing |
Front Artif Intell
December 2024
Alimentary Tract Research Center, Clinical Sciences Research Institute, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
One of the foremost causes of global healthcare burden is cancer of the gastrointestinal tract. The medical records, lab results, radiographs, endoscopic images, tissue samples, and medical histories of patients with gastrointestinal malignancies provide an enormous amount of medical data. There are encouraging signs that the advent of artificial intelligence could enhance the treatment of gastrointestinal issues with this data.
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December 2024
School of information engineering, Jingdezhen Ceramic University, Jingdezhen, China.
The early symptoms of hepatocellular carcinoma patients are often subtle and easily overlooked. By the time patients exhibit noticeable symptoms, the disease has typically progressed to middle or late stages, missing optimal treatment opportunities. Therefore, discovering biomarkers is essential for elucidating their functions for the early diagnosis and prevention.
View Article and Find Full Text PDFCurr Opin Neurol
February 2025
High Dimensional Neurology Group, UCL Queen Square Institute of Neurology, University College London, Russell Square House, Bloomsbury, London, UK.
Purpose Of Review: Though simple in its fundamental mechanism - a critical disruption of local blood supply - stroke is complicated by the intricate nature of the neural substrate, the neurovascular architecture, and their complex interactions in generating its clinical manifestations. This complexity is adequately described by high-resolution imaging with sensitivity not only to parenchymal macrostructure but also microstructure and functional tissue properties, in conjunction with detailed characterization of vascular topology and dynamics. Such descriptive richness mandates models of commensurate complexity only artificial intelligence could plausibly deliver, if we are to achieve the goal of individually precise, personalized care.
View Article and Find Full Text PDFISA Trans
January 2025
School of Electrical and Automation Engineering, East China Jiaotong University, Nanchang, 330013, Jiangxi, China; Key Laboratory of Advanced Control & Optimization of Jiangxi Province, Nanchang, 330013, Jiangxi, China. Electronic address:
Traditional data-driven models for predicting rare earth component content are primarily developed by relying on supervised learning methods, which suffer from limitations such as a lack of labeled data, lagging, and poor usage of a major amount of unlabeled data. This paper proposes a novel prediction approach based on the BiLSTM-Deep autoencoder enhanced traditional LSSVM algorithm, termed BiLSTM-DeepAE-LSSVM. This approach thoroughly exploits the implicit information contained in copious amounts of unlabeled data in the rare earth production process, thereby improving the traditional supervised prediction method and increasing the accuracy of component content predictions.
View Article and Find Full Text PDFBiol Pharm Bull
January 2025
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
As unexpected adverse events and successful drug repositioning have shown, drug effects are complex and include aspects not recognized by developers. How can we understand these unrecognized drug effects? Drug effects can be numerized by encompassing biological responses to drugs. For instance, the transcriptome data of cultured cells and toxicopathological images of mice treated with a compound represent the effects of the compound in vitro and in vivo, respectively.
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